2,4,6(1H,3H,5H)-Pyrimidinetrione,5-(1,3-dimethylbutyl)-5-ethyl-

名称

[ CAS 号 ]:
2964-06-9

[ 英文名 ]:
2,4,6(1H,3H,5H)-Pyrimidinetrione,5-(1,3-dimethylbutyl)-5-ethyl-

[英文别名 ]:

DMBEB
5-Aethyl-5-(1,3-dimethyl-butyl)-barbitursaeure
5-ethyl-5-(1,3-dimethylbutyl)-5-barbituric acid
Diberal
5-ethyl-5-(1',3'-dimethylbutyl)barbituric acid
5-(1,3-Dimethylbutyl)-5-ethylbarbituric acid

物理化学性质

[ 密度 ]:
1.063g/cm3

[ 分子式 ]:
C₁₂H₂₀N₂O₃

[ 分子量 ]:
240.29900

[ 精确质量 ]:
240.14700

[ PSA ]:
75.27000

[ LogP ]:
2.08860

[ 折射率 ]:
1.465

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CQ4060000

CHEMICAL NAME :: Barbituric acid, 5-(1,3-dimethylbutyl)-5-ethyl-

CAS REGISTRY NUMBER :: 2964-06-9

LAST UPDATED :: 199107

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C12-H20-N2-O3

MOLECULAR WEIGHT :: 240.34

WISWESSER LINE NOTATION :: T6VMVMV FHJ FY1&1Y1&1 F2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 75 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,31,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 70 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,31,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 17 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,31,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 10 mg/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,31,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 2500 ug/kg

TOXIC EFFECTS :: Brain and Coverings - recordings from specific areas of CNS Behavioral - convulsions or effect on seizure threshold Behavioral - excitement

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 1,31,1959

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 7 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 58,1354,1936

安全信息

[ 海关编码 ]:
2933540000

合成路线

详细合成路线

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海关

[ 海关编码 ]: 2933540000

[ 中文概述 ]:
2933540000 其他丙二酰脲（巴比土酸）的衍生物以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933540000 other derivatives of malonylurea (barbituric acid); salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:20.0%