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2-氨基噻唑-4-乙酸

2-氨基噻唑-4-乙酸用途

【用途一】
用于头孢类药物的制造，是头孢替安的中间体
【用途二】
头孢替安的中间体。

2-氨基噻唑-4-乙酸名称

[ CAS 号 ]:
29676-71-9

[ 中文名 ]:
2-氨基噻唑-4-乙酸

[ 英文名 ]:
2-Amino-4-thiazoleacetic acid

[中文别名 ]:

[英文别名 ]:

4-Thiazoleacetic acid, 2-amino-
2-Aminothiazol-4-acetic acid
2-(2-Aminothiazol-4-yl)acetic acid
(2-Imino-2,3-dihydro-1,3-thiazol-4-yl)acetic acid
2-aminothiazole-4-acetic acid
2-Amino-4-thiazoleacetic acid
(2-Aminothiazole-4-YL)-Acetic Acid
(2-Amino-4-thiazolyl)acetic Acid
MFCD00010068
(2-ammonio-1,3-thiazol-4-yl)acetate

2-氨基噻唑-4-乙酸物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
399.0±17.0 °C at 760 mmHg

[ 熔点 ]:
130 °C (dec.)(lit.)

[ 分子式 ]:
C₅H₆N₂O₂S

[ 分子量 ]:
158.178

[ 闪点 ]:
195.1±20.9 °C

[ 精确质量 ]:
158.014999

[ PSA ]:
104.45000

[ LogP ]:
-0.33

[ 外观性状 ]:
近乎于白色至淡米色结晶粉末

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.671

[ 储存条件 ]:
Refrigerator

[ 水溶解性 ]:
6.5 g/L (20 ºC)

2-氨基噻唑-4-乙酸MSDS

2-氨基噻唑-4-乙酸安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2942000000

2-氨基噻唑-4-乙酸合成路线

2-氨基噻唑-4-乙酸上下游产品

2-氨基噻唑-4-乙酸上游产品

2-氨基噻唑-4-乙酸下游产品

2-氨基噻唑-4-乙酸制备

1、用氯代或溴代乙酰基乙酸乙酯与硫脲缩合，然后水解制得。

2-氨基噻唑-4-乙酸海关

[ 海关编码 ]: 2934100090

[ 中文概述 ]:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-氨基噻唑-4-乙酸文献

Aqua-bis(2-amino-1,3-thia-zole-4-acetato-κO,N)nickel(II).

Acta Crystallogr. Sect. E Struct. Rep. Online 65(Pt 6) , m666, (2009)

In the crystal structure of the title compound, [Ni(C(5)H(5)N(2)O(2)S)(2)(H(2)O)], the Ni(II) cation is located on a twofold rotation axis and chelated by two 2-amino-1,3-thia-zole-4-acetate (ata) ani...

Poly (2-amino-4-thiazoleacetic acid)/multiwalled carbon nanotubes modified glassy carbon electrodes for the electrochemical detection of copper (II). Zhao H, et al.

Electrochim. Acta 55(7) , 256-63, (2010)

Electrochemical synthesis and characterization of a novel thiazole-based copolymer and its application in biosensor. Xue Y, et al.

Electrochim. Acta 59 , 256-63, (2012)

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