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4-苄基哌啶

4-苄基哌啶名称

[ CAS 号 ]:
31252-42-3

[ 中文名 ]:
4-苄基哌啶

[ 英文名 ]:
4-Benzylpiperidine

[中文别名 ]:

α-(4-哌啶基)甲苯

[英文别名 ]:

4-Benzyl-piperidine
4-benzylpiperazine
4-benzylpyperidine
4-(phenylmethyl)piperidine
4-Benzylpiperidine
Piperidine,4-(phenylmethyl)
Piperidine,4-benzyl
EINECS 250-535-0
MFCD00006006
Phenyl(4-piperidyl)methane

4-苄基哌啶物理化学性质

[ 密度 ]:
0.997 g/mL at 25 °C(lit.)

[ 沸点 ]:
279 °C(lit.)

[ 熔点 ]:
6-7 °C(lit.)

[ 分子式 ]:
C₁₂H₁₇N

[ 分子量 ]:
175.27000

[ 闪点 ]:
>230 °F

[ 精确质量 ]:
175.13600

[ PSA ]:
12.03000

[ LogP ]:
2.55750

[ 折射率 ]:
n20/D 1.537(lit.)

4-苄基哌啶MSDS

4-苄基哌啶毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM4728000

CHEMICAL NAME :: Piperidine, 4-benzyl-

CAS REGISTRY NUMBER :: 31252-42-3

BEILSTEIN REFERENCE NO. :: 0132339

LAST UPDATED :: 199701

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C12-H17-N

MOLECULAR WEIGHT :: 175.30

WISWESSER LINE NOTATION :: T6MTJ D1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01587

4-苄基哌啶安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
TM4728000

[ 海关编码 ]:
2933399090

4-苄基哌啶合成路线

4-苄基哌啶上下游产品

4-苄基哌啶上游产品

4-苄基哌啶下游产品

4-苄基哌啶海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-苄基哌啶文献

Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine.

J. Pharmacol. Exp. Ther. 329(1) , 272-81, (2009)

Monoamine releasers constitute one class of drugs currently under investigation as potential agonist medications for the treatment of cocaine dependence. The efficacy and safety of monoamine releasers...

Quantitative investigation on the metabolism of 1,3-butadiene and of its oxidized metabolites in once-through perfused livers of mice and rats.

Toxicol. Sci. 114(1) , 25-37, (2010)

The industrial chemical 1,3-butadiene (BD) is a potent carcinogen in mice and a weak one in rats. This difference is generally related to species-specific burdens by the metabolites 1,2-epoxy-3-butene...

Time-dependent inhibition of rat brain monoamine oxidase by an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine.

Neurosci. Lett. 70(2) , 255-60, (1986)

Inhibitory effects of some MPTP and MPP+ analogues on rat brain MAO activity were studied to further clarify the structure-activity relationships of MPTP neurotoxicity. Of the analogues tested, 4-(4-c...

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