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7-甲氧基吲哚

7-甲氧基吲哚用途

是医药中间体。

7-甲氧基吲哚名称

[ CAS 号 ]:
3189-22-8

[ 中文名 ]:
7-甲氧基吲哚

[ 英文名 ]:
7-Methoxyindole

[中文别名 ]:

7-甲氧吲哚

[英文别名 ]:

EINECS 221-690-1
1H-Indole, 7-methoxy-
indole, 7-methoxy-
7-METHOYINDOLE
7-Methoxy-1H-indole
7-OMe-indole
7-METHOYINDOLE-REGULATED
7-Methoxy-indol
7-Methoxylindole
7-Methoxyindole

7-甲氧基吲哚物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
297.8±13.0 °C at 760 mmHg

[ 熔点 ]:
147-150°C

[ 分子式 ]:
C₉H₉NO

[ 分子量 ]:
147.174

[ 闪点 ]:
109.2±10.1 °C

[ 精确质量 ]:
147.068420

[ PSA ]:
25.02000

[ LogP ]:
2.06

[ 外观性状 ]:
淡黄色液体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.637

[ 储存条件 ]:
−20°C

7-甲氧基吲哚MSDS

7-甲氧基吲哚安全信息

[ 符号 ]:

GHS05, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H315-H318-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933990090

7-甲氧基吲哚合成路线

7-甲氧基吲哚上下游产品

7-甲氧基吲哚上游产品

7-甲氧基吲哚下游产品

7-甲氧基吲哚海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

7-甲氧基吲哚文献

Tryptophan 2,3-dioxygenase (TDO) inhibitors. 3-(2-(pyridyl)ethenyl)indoles as potential anticancer immunomodulators.

J. Med. Chem. 54 , 5320, (2011)

Tryptophan catabolism mediated by indoleamine 2,3-dioxygenase (IDO) is an important mechanism of peripheral immune tolerance contributing to tumoral immune resistance. IDO inhibition is thus an active...

Identification of potent ITK inhibitors through focused compound library design including structural information

Bioorg. Med. Chem. Lett. 20 , 6998, (2010)

A series of novel compound libraries inhibiting interleukin-2 inducible T cell kinase (ITK) were designed, synthesized and evaluated. In the first design cycle two library scaffolds were identified sh...

Utilization of indole analogs by carrot and tobacco cell tryptophan synthase in vivo and in vitro.

Plant Physiol. 67(6) , 1101-4, (1981)

Twenty-three indole analogs were used to inhibit the growth of carrot and tobacco suspension cultures. The addition of tryptophan or indole partially reversed the inhibition of both cell lines only fo...

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