1-(3,4-dichlorobenzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidone

名称

[ CAS 号 ]:
34790-06-2

[ 英文名 ]:
1-(3,4-dichlorobenzyl)-3,4,5,6-tetrahydro-2(1H)-pyrimidone

[英文别名 ]:

eu-2841

物理化学性质

[ 密度 ]:
1.347g/cm3

[ 沸点 ]:
468.6ºC at 760mmHg

[ 分子式 ]:
C₁₁H₁₂Cl₂N₂O

[ 分子量 ]:
259.13200

[ 闪点 ]:
237.2ºC

[ 精确质量 ]:
258.03300

[ PSA ]:
35.83000

[ LogP ]:
2.48660

[ 折射率 ]:
1.585

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UW7568000

CHEMICAL NAME :: 2(1H)-Pyrimidinone, tetrahydro-1-((3,4-dichlorophenyl)methyl)-

CAS REGISTRY NUMBER :: 34790-06-2

BEILSTEIN REFERENCE NO. :: 0653915

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H12-Cl2-N2-O

MOLECULAR WEIGHT :: 259.15

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 815 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 69,1198,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 912 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 69,1198,1980

安全信息

[ 海关编码 ]:
2933599090

合成路线

详细合成路线

海关

[ 海关编码 ]: 2933599090

[ 中文概述 ]:
2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%