Prajmaline
Prajmaline名称
[ CAS 号 ]:
35080-11-6
[ 英文名 ]:
Prajmaline
[英文别名 ]:
- N-n-Propyl-21-epi-isoajmalinium Kation
- Prajmalium
- N-Propylajmaline
- N-Propyl-ajmalinium
Prajmaline物理化学性质
[ 分子式 ]:
C23H33N2O2+
[ 分子量 ]:
369.52000
[ 精确质量 ]:
369.25400
[ PSA ]:
43.70000
[ LogP ]:
2.50310
Prajmaline毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AX8155800
- CHEMICAL NAME :
- Ajmalanium, 17,21-dihydroxy-4-propyl-, (17R,21-alpha)-
- CAS REGISTRY NUMBER :
- 35080-11-6
- LAST UPDATED :
- 198602
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C23-H33-N2-O2
- MOLECULAR WEIGHT :
- 369.58
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1400 ug/kg
- TOXIC EFFECTS :
- Cardiac - other changes
- REFERENCE :
- PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 31,36,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 65500 ug/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 22,2329,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3400 ug/kg
- TOXIC EFFECTS :
- Behavioral - altered sleep time (including change in righting reflex) Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 22,2329,1974
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