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盐酸钩吻碱

盐酸钩吻碱名称

[ CAS 号 ]:
35306-33-3

[ 中文名 ]:
盐酸钩吻碱

[ 英文名 ]:
GELSEMINE HYDROCHLORIDE

[中文别名 ]:

胡曼鹼鹽酸鹽

[英文别名 ]:

Gelsemine,hydrochloride
Gelsemin,Hydrochlorid
Gelsemine,monohydrochloride
EINECS 252-504-7
Gelsemine HCl

盐酸钩吻碱物理化学性质

[ 沸点 ]:
493.4ºC at 760mmHg

[ 熔点 ]:
>300ºC

[ 分子式 ]:
C₂₀H₂₃ClN₂O₂

[ 分子量 ]:
358.86200

[ 闪点 ]:
252.2ºC

[ 精确质量 ]:
358.14500

[ PSA ]:
41.57000

[ LogP ]:
2.90550

[ 储存条件 ]:
库房低温,通风,干燥,与食品原料分开存放

盐酸钩吻碱毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LX9150000

CHEMICAL NAME :: Gelsemine, monohydrochloride

CAS REGISTRY NUMBER :: 35306-33-3

LAST UPDATED :: 199203

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H22-N2-O2.Cl-H

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 4 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: DUSA** "Dispensatory of the United States of America," 24th ed., Osol, A. and G.E. Farrar, Philadelphia, J.B. Lippincott Co., 1947 Volume(issue)/page/year: 24,497,1947

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Liver - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: ZEBLA3 Zeitschrift fuer Biologie. (Munich, Fed. Rep. Ger.) V.1-116, 1865-1971. Discontinued. Volume(issue)/page/year: 99,446,1939