2-Phenylbicyclo[2.2.1]heptane-2-carboxylic acid 2-(1-pyrrolidinyl)ethyl ester

名称

[ CAS 号 ]:
3570-06-7

[ 英文名 ]:
2-Phenylbicyclo[2.2.1]heptane-2-carboxylic acid 2-(1-pyrrolidinyl)ethyl ester

[英文别名 ]:

KR 363
Bicyclophenamine
KR 363 [German]

物理化学性质

[ 密度 ]:
1.128g/cm3

[ 沸点 ]:
438.3ºC at 760mmHg

[ 分子式 ]:
C₂₀H₂₇NO₂

[ 分子量 ]:
313.43400

[ 闪点 ]:
144.5ºC

[ 精确质量 ]:
313.20400

[ PSA ]:
29.54000

[ LogP ]:
3.32130

[ 折射率 ]:
1.563

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DT4780000

CHEMICAL NAME :: Bicyclo(2.2.1)heptane-2-carboxylic acid, 2-phenyl-, 2-(pyrrolidino)ethyl ester

CAS REGISTRY NUMBER :: 3570-06-7

LAST UPDATED :: 199712

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C20-H27-N-O2

MOLECULAR WEIGHT :: 313.48

WISWESSER LINE NOTATION :: L55 ATJ CR& CVO2- AT5NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 308 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 38 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 128,204,1960

安全信息

[ 海关编码 ]:
2933990090

海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%