17beta-Estradiol 3-tetrahydropyranyl ether
名称
[ CAS 号 ]:
3589-90-0
[ 英文名 ]:
17beta-Estradiol 3-tetrahydropyranyl ether
[英文别名 ]:
- 17beta-Estradiol 3-tetrahydropyranyl ether
- RS-2290
物理化学性质
[ 密度 ]:
1.16g/cm3
[ 沸点 ]:
508.8ºC at 760 mmHg
[ 分子式 ]:
C23H32O3
[ 分子量 ]:
356.49800
[ 闪点 ]:
261.5ºC
[ 精确质量 ]:
356.23500
[ PSA ]:
38.69000
[ LogP ]:
5.16010
[ 折射率 ]:
1.585
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KG7742000
- CHEMICAL NAME :
- Estra-1,3,5(10)-trien-3-ol, 17-beta-(tetrahydro-2H-pyran-2-yloxy)-
- CAS REGISTRY NUMBER :
- 3589-90-0
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C23-H32-O3
- MOLECULAR WEIGHT :
- 356.55
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 26400 ng/kg
- SEX/DURATION :
- female 3 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 20,211,1969
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 3 mg/kg
- SEX/DURATION :
- female 1-3 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 20,211,1969
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 1500 ug/kg
- SEX/DURATION :
- female 1-3 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
- REFERENCE :
- FESTAS Fertility and Sterility. (American Fertility Soc., 608 13th Ave. S, Birmingham, AL 35282) V.1- 1950- Volume(issue)/page/year: 20,211,1969
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