地芬诺酯盐酸盐

地芬诺酯盐酸盐用途

用于急、慢性功能性腹泻及慢性肠炎等包装: 25KG/DRUM

地芬诺酯盐酸盐名称

[ CAS 号 ]:
3810-80-8

[ 中文名 ]:
地芬诺酯盐酸盐

[ 英文名 ]:
diphenoxylate hydrochloride

[中文别名 ]:

盐酸地芬诺酯(苯乙哌啶粉)

[英文别名 ]:

DIPHENOXYLATE HYDROCHLORIDE
DIPHENOXYLATE HYDROCHLORIDE ANTIPERISTAL TIC,ANTI
DIPHENOXYLATE HCL
r1132

地芬诺酯盐酸盐物理化学性质

[ 沸点 ]:
602.3ºC at 760mmHg

[ 熔点 ]:
220.0-222.5ºC

[ 分子式 ]:
C₃₀H₃₃ClN₂O₂

[ 分子量 ]:
489.048

[ 闪点 ]:
318ºC

[ 精确质量 ]:
488.223053

[ PSA ]:
53.33000

[ LogP ]:
6.22318

[ 储存条件 ]:
库房低温,通风,干燥,与食品原料分开存放

[ 水溶解性 ]:
Very slightly soluble in water, freely soluble in methylene chloride, sparingly soluble in ethanol (96 per cent).

地芬诺酯盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NS5300000

CHEMICAL NAME :: Isonipecotic acid, 1-(3-cyano-3,3-diphenylpropyl)-4-phenyl-, ethyl ester, hydrochloride

CAS REGISTRY NUMBER :: 3810-80-8

LAST UPDATED :: 199712

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C30-H32-N2-O2.Cl-H

MOLECULAR WEIGHT :: 489.10

WISWESSER LINE NOTATION :: T6NTJ A2XR&R&CN DVO2 DR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 221 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1633,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1636,1974

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >160 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 24,1636,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3182 No. of Facilities: 105 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 8242 (estimated) No. of Female Employees: 7235 (estimated)

地芬诺酯盐酸盐安全信息

[ 危险品运输编码 ]:
UN 1544

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)