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[His(π-Methyl)2]-LH-RH

[His(π-Methyl)2]-LH-RH名称

[ CAS 号 ]:
38343-58-7

[ 中文名 ]:
[His(π-Methyl)2]-LH-RH

[ 英文名 ]:
(His(3-Me)2)-LHRH trifluoroacetate salt

[中文别名 ]:

(HIS(1-ME)2)-LHRH

[英文别名 ]:

(His(3-Me)2)-LHRH

[His(π-Methyl)2]-LH-RH物理化学性质

[ 分子式 ]:
C₅₆H₇₇N₁₇O₁₃

[ 分子量 ]:
1196.32000

[ 精确质量 ]:
1195.59000

[ PSA ]:
461.27000

[ LogP ]:
1.11780

[His(π-Methyl)2]-LH-RHMSDS

详细MSDS(安全技术说明书)

[His(π-Methyl)2]-LH-RH安全信息

[ WGK德国 ]:
3

[His(π-Methyl)2]-LH-RH文献

Haploinsufficiency of Dmxl2, encoding a synaptic protein, causes infertility associated with a loss of GnRH neurons in mouse.

PLoS Biol. 12(9) , e1001952, (2014)

Characterization of the genetic defects causing gonadotropic deficiency has made a major contribution to elucidation of the fundamental role of Kisspeptins and Neurokinin B in puberty onset and reprod...

R31C GNRH1 mutation and congenital hypogonadotropic hypogonadism.

PLoS ONE 8(7) , e69616, (2013)

Normosmic congenital hypogonadotropic hypogonadism (nCHH) is a rare reproductive disease leading to lack of puberty and infertility. Loss-of-function mutations of GNRH1 gene are a very rare cause of a...

Characterization of 12 GnRH peptide agonists - a kinetic perspective.

Br. J. Pharmacol. 173(1) , 128-41, (2016)

Drug-target residence time is an important, yet often overlooked, parameter in drug discovery. Multiple studies have proposed an increased residence time to be beneficial for improved drug efficacy an...

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