ICR 340
ICR 340名称
[ CAS 号 ]:
38915-28-5
[ 英文名 ]:
ICR 340
ICR 340物理化学性质
[ 分子式 ]:
C20H25Cl3N4O
[ 分子量 ]:
443.79800
[ 精确质量 ]:
442.10900
[ PSA ]:
50.28000
[ LogP ]:
5.68270
ICR 340毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DI2400000
- CHEMICAL NAME :
- Benzo(b)(1,5)naphthyridine, 7-chloro-10-(3-(N-(2-chloroethyl)-N-ethyl)aminopropyl amino)- 2-methoxy-, dihydrochloride
- CAS REGISTRY NUMBER :
- 38915-28-5
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C20-H24-Cl2-N4-O.2Cl-H
- MOLECULAR WEIGHT :
- 480.30
- WISWESSER LINE NOTATION :
- T C666 BN GNJ FO1 IM3N2&2G MG &GH 2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD20 - Lethal Dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3737 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 7 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4800 ug/kg
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in mammalian somatic cells
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 1 umol/L
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 39,4875,1979
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相关化合物
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