二氢叶酸

更新时间：2024-01-02 10:40:26

二氢叶酸结构式	常用名	二氢叶酸	英文名	Dihydrofolic acid
	CAS号	4033-27-6	分子量	443.41300
	密度	1.69g/cm3	沸点	N/A
	分子式	C₁₉H₂₁N₇O₆	熔点	N/A
	MSDS	中文版美版	闪点	N/A
	符号	GHS07	信号词	Warning

二氢叶酸用途

Dihydrofolic acid 是一种叶酸衍生物,由二氢叶酸还原酶作用转化为四氢叶酸。

中文名	二氢叶酸
英文名	dihydrofolic acid
英文别名	更多

描述	Dihydrofolic acid 是一种叶酸衍生物,由二氢叶酸还原酶作用转化为四氢叶酸。
相关类别	研究领域 >> 其他天然产物 >> 其他
靶点	Human Endogenous Metabolite

密度	1.69g/cm3
分子式	C₁₉H₂₁N₇O₆
分子量	443.41300
精确质量	443.15500
PSA	211.89000
LogP	0.62870
折射率	1.762
储存条件	-20°C

符号	GHS07
信号词	Warning
危害声明	H315-H319-H335
警示性声明	P261-P305 + P351 + P338
个人防护装备	dust mask type N95 (US);Eyeshields;Gloves
危害码 (欧洲)	Xi: Irritant;
风险声明 (欧洲)	36/37/38
安全声明 (欧洲)	26-36
危险品运输编码	NONH for all modes of transport

叶酸

59-30-3

~82%

二氢叶酸

4033-27-6

文献：Khilifa; Ganguly; Bieri; Viscontini Helvetica Chimica Acta, 1980 , vol. 63, # 8 p. 2554 - 2558

未登录

142811-49-2

二氢叶酸

4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

2-amino-6[[2'(R...

142811-46-9

二氢叶酸

4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

2-amino-6-[[2'(...

142811-47-0

二氢叶酸

4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

未登录

142811-48-1

二氢叶酸

4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

N-(4-((2(R)-(be...

142811-50-5

二氢叶酸

4033-27-6

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

N-(4-氨基甲酰)-L-谷氨酸

4271-30-1

二氢叶酸

4033-27-6

文献：Shiota; Disraely Biochimica et Biophysica Acta, 1961 , vol. 52, p. 467,468 Full Text Show Details Shiota Archives of Biochemistry, 1959 , vol. 80, p. 155,156

N-[4-[[2(R)-ami...

142811-51-6

四氢叶酸

135-16-0

(S)-2-(4-(((S)-...

142811-42-5

Arfolitixorin

31690-11-6

详细

文献：Bailey, Steven W.; Chandrasekaran, Rama Y.; Ayling, June E. Journal of Organic Chemistry, 1992 , vol. 57, # 16 p. 4470 - 4477

二氢叶酸上游产品 5
CAS号59-30-3 叶酸 CAS号142811-46-9 2-amino-6[[2'(R... CAS号142811-47-0 2-amino-6-[[2'(... CAS号4271-30-1 N-(4-氨基甲酰)-L-谷氨酸
CAS号142811-51-6 N-[4-[[2(R)-ami...
二氢叶酸下游产品 1
CAS号135-16-0 四氢叶酸

Synthetic polyglutamylation of dual-functional MTX ligands for enhanced combined cytotoxicity of poly(I:C) nanoplexes.

Mol. Pharm. 11(8) , 2631-9, (2014)

The antifolate drug methotrexate (MTX) can serve as a dual-functional ligand in antitumoral drug delivery, inducing both a folate receptor mediated cellular uptake and an intracellular cytotoxic actio...

A domino effect in antifolate drug action in Escherichia coli.

Nat. Chem. Biol. 4 , 602-8, (2008)

Mass spectrometry technologies for measurement of cellular metabolism are opening new avenues to explore drug activity. Trimethoprim is an antibiotic that inhibits bacterial dihydrofolate reductase (D...

Methotrexate-gelonin conjugate - an inhibitor of MCF-7 cells expressing the dihydrofolate receptor.

Biol. Chem. 395(12) , 1461-6, (2014)

An immunotoxin composed of gelonin, a basic ribosome-inactivating protein, type I of 30 kDa, isolated from the seeds of the Indian plant Gelonium multiflorum and methotrexate (MTX) has been studied as...

7,8-Dihydropteroyl-L-glutamic acid Dihydropteroyl-L-glutamic acid

DIHYDROFOLIC ACID