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ω,ω'-乙二硫二磺酸

ω,ω'-乙二硫二磺酸名称

[ CAS 号 ]:
45127-11-5

[ 中文名 ]:
辅酶 M

[ 英文名 ]:
Coenzyme M

[英文别名 ]:

Ethanesulfonic acid, 2,2'-dithiobis-
2,2'-Dithiodiethanesulfonic acid
2,2'-dithiobisethanesulfonic acid
Ethanesulfonic acid,2,2'-dithiobis
2,2'-Disulfanediyldiethanesulfonic acid
Coenzyme

ω,ω'-乙二硫二磺酸物理化学性质

[ 密度 ]:
1.8±0.1 g/cm3

[ 分子式 ]:
C₄H₁₀O₆S₄

[ 分子量 ]:
282.379

[ 精确质量 ]:
281.936005

[ PSA ]:
176.10000

[ LogP ]:
-1.83

[ 折射率 ]:
1.637

ω,ω'-乙二硫二磺酸安全信息

[ 海关编码 ]:
2930909090

ω,ω'-乙二硫二磺酸合成路线

详细合成路线

ω,ω'-乙二硫二磺酸上下游产品

ω,ω'-乙二硫二磺酸上游产品

ω,ω'-乙二硫二磺酸下游产品

ω,ω'-乙二硫二磺酸海关

[ 海关编码 ]: 2930909090

[ 中文概述 ]:
2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

ω,ω'-乙二硫二磺酸文献

Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N.

Cancer Chemother. Pharmacol. 67(2) , 381-91, (2011)

Previous studies from our laboratory have identified a role for gamma-glutamyl transpeptidase (GGT) in BNP7787 (disodium 2,2'-dithio-bis ethane sulfonate, dimesna, Tavocept™)-mediated cisplatin nephro...

Phase II randomized study of dose-dense docetaxel and cisplatin every 2 weeks with pegfilgrastim and darbepoetin alfa with and without the chemoprotector BNP7787 in patients with advanced non-small cell lung cancer (CALGB 30303).

J. Thorac. Oncol. 3(10) , 1159-65, (2008)

We investigated dose-dense docetaxel and cisplatin in patients with measurable non-small cell lung cancer in a randomized phase II study without [A] or with [B] a putative chemoprotective agent, BNP77...

New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent.

Cancer Chemother. Pharmacol. 52 Suppl 1 , S3-15, (2003)

Any approach applied to drug discovery and development by the medical community and pharmaceutical industry has a direct impact on the future availability of improved, novel, and curative therapies fo...

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