夹竹桃苷元
夹竹桃苷元名称
[ CAS 号 ]:
465-15-6
[ 中文名 ]:
夹竹桃苷元
[ 英文名 ]:
Card-20(22)-enolide,16-(acetyloxy)-3,14-dihydroxy-, (3b,5b,16b)-
[英文别名 ]:
- gitoxigenin 16-acetate
- olendrigenin
- Oleandrigenin
夹竹桃苷元物理化学性质
[ 密度 ]:
1.26g/cm3
[ 沸点 ]:
584.6ºC at 760mmHg
[ 分子式 ]:
C25H36O6
[ 分子量 ]:
432.55000
[ 闪点 ]:
194.9ºC
[ 精确质量 ]:
432.25100
[ PSA ]:
93.06000
[ LogP ]:
3.14590
[ 蒸汽压 ]:
4.21E-16mmHg at 25°C
[ 折射率 ]:
1.578
[ 储存条件 ]:
2-8°C
夹竹桃苷元毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- FH5400000
- CHEMICAL NAME :
- 5-beta-Card-20(22)-enolide, 3-beta,14,16-beta-trihydroxy-, 16-acetate
- CAS REGISTRY NUMBER :
- 465-15-6
- LAST UPDATED :
- 199009
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C25-H36-O6
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 216 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 5,988,1962
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Bird - pigeon
- DOSE/DURATION :
- 950 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 8,18,1960 *** REVIEWS *** TOXICOLOGY REVIEW 85ELDJ "Die Herzwirksamen Glykoside," Baumgarten, G., and W. Forster, Leipzig, Ger. Dem. Rep., VEB Georg Thieme, 1963 Volume(issue)/page/year: -,104,1963
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