(8β)-2-Bromo-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carbox amide
名称
[ CAS 号 ]:
478-84-2
[ 英文名 ]:
(8β)-2-Bromo-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carbox amide
[英文别名 ]:
- Bromolysergide
- 6-Bromo-3-pyridylmethyl bromide
- 2-bromo-lysergide
- 2-bromo-5-pyridylmethyl bromide
- 2-Brom-lysergsaeurediethylamid
- 2-bromo-5-bromoethylpyridine
- 2-bromo-5-bromomethylpyridine
- 2-bromo-5R,8R-lysergic acid diethyl amide
物理化学性质
[ 密度 ]:
1.44g/cm3
[ 沸点 ]:
580.7ºC at 760mmHg
[ 分子式 ]:
C20H24BrN3O
[ 分子量 ]:
402.32800
[ 闪点 ]:
305ºC
[ 精确质量 ]:
401.11000
[ PSA ]:
39.34000
[ LogP ]:
3.60640
[ 蒸汽压 ]:
1.77E-13mmHg at 25°C
[ 折射率 ]:
1.676
[ 储存条件 ]:
库房通风低温干燥,与食品原料类分开存放
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KE2625000
- CHEMICAL NAME :
- Ergoline-8-beta-carboxamide, 2-bromo-9,10-didehydro-N,N-diethyl-6-methyl-
- CAS REGISTRY NUMBER :
- 478-84-2
- LAST UPDATED :
- 199106
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C20-H26-Br-N3-O
- MOLECULAR WEIGHT :
- 404.40
- WISWESSER LINE NOTATION :
- T C6656 1A P GN LN CUTT&&J EVN2&2 G1 KE L1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 75 ug/kg
- TOXIC EFFECTS :
- Vascular - regional or general arteriolar or venous dilation
- REFERENCE :
- PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 1,20,1959
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Nutritional and Gross Metabolic - body temperature increase
- REFERENCE :
- ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 66,668,1957 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 2 ug/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 158,265,1967
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 2 ug/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - homeostasis Reproductive - Specific Developmental Abnormalities - other developmental abnormalities
- REFERENCE :
- SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 158,265,1967
合成路线
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐乾明
产品详情：化合物 T26910
查看所有供应商请点击：
(8β)-2-Bromo-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carbox amide供应商
热门化合物
CAS号[478-84-2]化源网提供[(8β)-2-Bromo-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carbox amide]MSDS、说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。>>电脑版：(8β)-2-Bromo-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carbox amide
标题：478-84-2_CAS号:478-84-2_(8β)-2-Bromo-N,N-diethyl-6-methyl-9,10-didehydroergoline-8-carbox amide - 化源网 地址：https://www.chemsrc.com/amp/cas/478-84-2_969986.html