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7-氨基氯硝西泮

7-氨基氯硝西泮名称

[ CAS 号 ]:
4959-17-5

[ 中文名 ]:
7-氨基氯硝西泮

[ 英文名 ]:
7-Aminoclonazepam(CRM)

[英文别名 ]:

7-氨基氯硝西泮物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
533.6±60.0 °C at 760 mmHg

[ 熔点 ]:
226-228ºC

[ 分子式 ]:
C₁₅H₁₂ClN₃O

[ 分子量 ]:
285.728

[ 闪点 ]:
276.5±32.9 °C

[ 精确质量 ]:
285.066895

[ PSA ]:
67.48000

[ LogP ]:
0.72

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.696

[ 储存条件 ]:
-20°C

7-氨基氯硝西泮安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H302 + H332-H319

[ 警示性声明 ]:
P210-P305 + P351 + P338

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
UN 1648 3 / PGII

7-氨基氯硝西泮合成路线

详细合成路线

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7-氨基氯硝西泮文献

Extraction and analysis of clonazepam and 7-aminoclonazepam in whole blood using a dual internal standard methodology.

Forensic Sci. Int. 166(2-3) , 209-17, (2007)

In this paper, a simple and robust method for the determination of clonazepam and its primary metabolite (7-aminoclonazepam) in whole blood is described. Clonazepam (klonopin) is a popular prescriptio...

A highly sensitive method for the determination of 7-aminonitrazepam, a metabolite of nitrazepam, in human urine using high-performance electrospray liquid chromatography tandem mass spectrometry.

Biomed. Chromatogr. 23(7) , 740-4, (2009)

A highly sensitive method has been developed for the determination of urinary 7-aminonitrazepam (7-ANZP), the major metabolite of nitrazepam, using high-performance electrospray liquid chromatography ...

Simultaneous determination and quantification of 12 benzodiazepines in serum or whole blood using UPLC/MS/MS.

Methods Mol. Biol. 603 , 107-19, (2010)

The benzodiazepines are a large, commonly prescribed family of psychoactive drugs. We describe a method permitting the simultaneous detection and quantification of 12 benzodiazepines in serum using ul...

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