HYPOGLYCINB
HYPOGLYCINB名称
[ CAS 号 ]:
502-37-4
[ 英文名 ]:
HYPOGLYCINB
[英文别名 ]:
- Hypoglyin-B
- (S)-2-L-alanylamino-butyric acid
- (S)-2-L-Alanylamino-buttersaeure
- L-2-(L-2-Amino-propionylamino)-buttersaeure
- N-L-Alanyl-L-2-amino-buttersaeure
HYPOGLYCINB物理化学性质
[ 密度 ]:
1.33g/cm3
[ 沸点 ]:
592.8ºC at 760mmHg
[ 分子式 ]:
C12H18N2O5
[ 分子量 ]:
270.28200
[ 闪点 ]:
312.3ºC
[ 精确质量 ]:
270.12200
[ PSA ]:
133.21000
[ LogP ]:
1.25470
[ 折射率 ]:
1.562
HYPOGLYCINB毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AY6330000
- CHEMICAL NAME :
- Alanine, N-L-gamma-glutamyl-3-(methylenecyclopropyl)-
- CAS REGISTRY NUMBER :
- 502-37-4
- BEILSTEIN REFERENCE NO. :
- 3162184
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C12-H18-N2-O5
- MOLECULAR WEIGHT :
- 270.32
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 121,272,1957
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 160 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 121,272,1957
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 25 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Endocrine - hypoglycemia
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 121,272,1957 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intrauterine
- DOSE :
- 500 ug/kg
- SEX/DURATION :
- female 14 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system
- REFERENCE :
- TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 4,246,1971
HYPOGLYCINB合成路线
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