CAINDEXNAME:8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC

名称

[ CAS 号 ]:
50372-80-0

[ 英文名 ]:
CAINDEXNAME:8-AZABICYCLO[3.2.1]OCTANE-2-CARBOXYLIC

[英文别名 ]:

WIN35,065-2

物理化学性质

[ 密度 ]:
1.099g/cm3

[ 沸点 ]:
350.2ºC at 760 mmHg

[ 分子式 ]:
C₂₀H₂₇NO₈

[ 分子量 ]:
409.43000

[ 闪点 ]:
121.3ºC

[ 精确质量 ]:
409.17400

[ PSA ]:
144.60000

[ LogP ]:
0.24120

[ 折射率 ]:
1.54

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CL5603110

CHEMICAL NAME :: 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 8-methyl-3-phenyl-, methyl ester, (1R-(exo,exo))-

CAS REGISTRY NUMBER :: 50372-80-0

LAST UPDATED :: 199009

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C16-H21-N-O2

MOLECULAR WEIGHT :: 259.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 63 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1260,1973

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2933990090

上下游产品

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海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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Saturable (3H)cocaine binding in central nervous system of mouse.

Life Sci. 27(12) , 1055-62, (1980)

Synthesis and transporter binding properties of 2,3-diphenyltropane stereoisomers. Comparison to 3beta-phenyltropane-2beta-carboxylic acid esters.

J. Med. Chem. 40(8) , 1247-51, (1997)

2beta,3beta-Diphenyl-(5), 2alpha,3alpha-diphenyl-(6), and 2alpha,3beta-diphenyltropane (3) as well as 2,3-diphenyltrop-2-ene (4) were prepared in racemic form and assayed for inhibition of radioligand...

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