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卡米罗芬

卡米罗芬用途

Camylofin是一种抗胆碱剂, 是一种平滑肌松弛剂。

卡米罗芬名称

[ CAS 号 ]:
54-30-8

[ 中文名 ]:
卡米罗芬

[ 英文名 ]:
Camylofine

[英文别名 ]:

Adopon
Camylofine
Sintespasmil
Acamylophenine
Spasmocan
Novospasmin
Camylopin
Navadyl
Belosin
Camylofin

卡米罗芬生物活性

[ 描述 ]:

Camylofin是一种抗胆碱剂, 是一种平滑肌松弛剂。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 由mAChR

信号通路 >> 神经信号通路 >> mAChR

研究领域 >> 神经疾病

[相关活性小分子]

卡米罗芬物理化学性质

[ 密度 ]:
0.987g/cm3

[ 沸点 ]:
408.4ºC at 760mmHg

[ 熔点 ]:
25°C

[ 分子式 ]:
C₁₉H₃₂N₂O₂

[ 分子量 ]:
320.47000

[ 闪点 ]:
200.8ºC

[ 精确质量 ]:
320.24600

[ PSA ]:
41.57000

[ LogP ]:
3.63930

[ 折射率 ]:
1.502

[ 储存条件 ]:
-20°C，密闭，干燥

卡米罗芬MSDS

详细MSDS(安全技术说明书)

卡米罗芬毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MB9625000

CHEMICAL NAME :: Glycine, N-(2-(diethylamino)ethyl)-2-phenyl-, isopentyl ester

CAS REGISTRY NUMBER :: 54-30-8

BEILSTEIN REFERENCE NO. :: 2816984

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C19-H32-N2-O2

MOLECULAR WEIGHT :: 320.53

WISWESSER LINE NOTATION :: 2N2&2MYR&VO2Y1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DMWOAX Deutsche Medizinische Wochenschrift. (Stuttgart, Fed. Rep. Ger.) V.1-104, 1875-1979. Volume(issue)/page/year: 76,479,1951

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 76,1175,1956

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 610 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 59,113,1963

卡米罗芬安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
22

[ 安全声明 (欧洲) ]:
36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
MB9625000

[ 海关编码 ]:
2922499990

卡米罗芬海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

卡米罗芬文献

Determination of the analgesic components of Spasmomigraine tablet by liquid chromatography with ultraviolet detection.

J. AOAC Int. 90(1) , 94-101, (2007)

A procedure was developed for the determination of the analgesic components of Spasmomigraine tablets, which are ergotamine (I), propyphenazone (II), caffeine (III), camylofin (IV), and mecloxamine (V...

Use of anafortan intravenous injection for treatment of colicky pain.

J. Indian Med. Assoc. 98(8) , 479, 482, (2000)

Development and characterization of colon specific drug delivery system bearing 5-ASA and Camylofine dihydrochloride for the treatment of ulcerative colitis.

J. Drug Target. 18(8) , 589-601, (2010)

The treatment of ulcerative colitis (inflammatory bowel disease, IBD) has been achieved by using colon specific drug delivery system bearing 5-ASA and Camylofine dihydrochloride. Chitosan microspheres...

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