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硫代乙醇酸铵

硫代乙醇酸铵用途

【用途一】
用于测定铁的试剂及制药工业
【用途二】
在化妆品中用作卷发剂、营养液，起定型作用
【用途三】
光度试剂和掩蔽剂。测定铁、铝、银和锡等离子。卷发冷烫剂。

硫代乙醇酸铵名称

[ CAS 号 ]:
5421-46-5

[ 中文名 ]:
巯基乙酸铵

[ 英文名 ]:
Ammonium thioglycolate

[中文别名 ]:

[英文别名 ]:

azanium,2-sulfanylacetate
MFCD00137451
EINECS 226-540-9

硫代乙醇酸铵物理化学性质

[ 密度 ]:
1.311g/cm3

[ 沸点 ]:
115ºC

[ 熔点 ]:
-10ºC

[ 分子式 ]:
C₂H₇NO₂S

[ 分子量 ]:
109.14700

[ 闪点 ]:
99.8ºC

[ 精确质量 ]:
109.02000

[ PSA ]:
78.93000

[ 外观性状 ]:
无色至淡的粉红色液体

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
Miscible

硫代乙醇酸铵MSDS

详细MSDS(安全技术说明书)

硫代乙醇酸铵毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AI7525000

CHEMICAL NAME :: Acetic acid, mercapto-, monoammonium salt

CAS REGISTRY NUMBER :: 5421-46-5

LAST UPDATED :: 199712

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C2-H4-O2-S.H3-N

MOLECULAR WEIGHT :: 109.16

WISWESSER LINE NOTATION :: SH1VO &ZH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 165 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 97,349,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 175 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 97,349,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity)

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 97,349,1949 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83494 No. of Facilities: 4049 (estimated) No. of Industries: 4 No. of Occupations: 3 No. of Employees: 33142 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83494 No. of Facilities: 4016 (estimated) No. of Industries: 6 No. of Occupations: 5 No. of Employees: 41131 (estimated) No. of Female Employees: 30870 (estimated)

硫代乙醇酸铵安全信息

[ 符号 ]:

GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H290-H301-H317

[ 警示性声明 ]:
P280-P301 + P310

[ 个人防护装备 ]:
Eyeshields;Gloves

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
25-43

[ 安全声明 (欧洲) ]:
36/37-45

[ 危险品运输编码 ]:
2810

[ WGK德国 ]:
1

[ RTECS号 ]:
AI7525000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

硫代乙醇酸铵制备

1.主要采用中和法。以巯代乙醇酸和碳酸氢铵为原料，进行中和反应，然后经过滤而得。也可以氯乙酸、硫脲和氢氧化钡为原料制得硫代乙醇酸钡，再与铵盐反应而得。

硫代乙醇酸铵文献

Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors.

Am. J. Physiol. Regul. Integr. Comp. Physiol. 307(1) , R35-43, (2014)

β-mercaptoacetate (MA) is a drug known to block mitochondrial oxidation of medium- and long-chain fatty acids (FAs) and to stimulate feeding. Because MA-induced feeding is vagally dependent, it has be...

Preactivated thiomers for vaginal drug delivery vehicles.

Biomaterials 34(32) , 7811-8, (2013)

It was the purpose of this study to design and evaluate a chitosan derivative as mucoadhesive excipient for vaginal drug delivery systems. The chemical modification of chitosan was achieved by conjuga...

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