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丁二酰氯

丁二酰氯用途

骨骼肌松弛药，用作全身麻醉辅助用药
该品是合成树脂、涂料、药物氯化琥珀胆碱的中间体。

丁二酰氯名称

[ CAS 号 ]:
543-20-4

[ 中文名 ]:
丁二酰氯

[ 英文名 ]:
SUCCINYL CHLORIDE

[中文别名 ]:

[英文别名 ]:

MFCD00000749
butanedioyl dichloride
EINECS 208-838-0

丁二酰氯物理化学性质

[ 密度 ]:
1.407 g/mL at 25 °C(lit.)

[ 沸点 ]:
190 °C(lit.)

[ 熔点 ]:
16 °C

[ 分子式 ]:
C₄H₄Cl₂O₂

[ 分子量 ]:
154.97900

[ 闪点 ]:
170 °F

[ 精确质量 ]:
153.95900

[ PSA ]:
34.14000

[ LogP ]:
1.29740

[ 外观性状 ]:
液体;White or Colorless to Light orange to Yellow powder to lump to clear liquid

[ 折射率 ]:
n20/D 1.468(lit.)

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、碱类分开存放

[ 水溶解性 ]:
可溶于：乙醚,丙酮,苯

丁二酰氯MSDS

详细MSDS(安全技术说明书)

丁二酰氯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: WN4900000

CHEMICAL NAME :: Succinyl chloride

CAS REGISTRY NUMBER :: 543-20-4

BEILSTEIN REFERENCE NO. :: 0507064

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H4-Cl2-O2

MOLECULAR WEIGHT :: 154.98

WISWESSER LINE NOTATION :: GV2VG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 62500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 4,111,1952 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7226 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

丁二酰氯安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H314

[ 补充危害声明 ]:
Reacts violently with water.

[ 警示性声明 ]:
P280-P305 + P351 + P338-P310

[ 个人防护装备 ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
C:Corrosive;

[ 风险声明 (欧洲) ]:
R34

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3265 8/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
WN4900000

[ 包装等级 ]:
II

[ 危险类别 ]:
8

[ 海关编码 ]:
2923900090

丁二酰氯制备

由丁二酸与五氯化磷反应而得。将丁二酸、五氯化磷和无水氯仿依次加入反应锅，激烈反应转缓时，加热至回流，待反应物全部变液体时蒸去低沸物回收氯仿，然后减压蒸馏回收氧氯化磷，将残液进一步加热，继续减压蒸馏，收集95-110℃（2.67kPa）馏分，即为丁二酰氯。收率88%左右。

丁二酰氯海关

[ 海关编码 ]: 2917190090

[ 中文概述 ]:
2917190090 其他无环多元羧酸. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 对苯二甲酸请注明4-CBA值, 对苯二甲酸请注明P-TL酸值, 对苯二甲酸请注明色度, 对苯二甲酸请注明水分

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%