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5-氨基乙酰丙酸盐酸盐

5-氨基乙酰丙酸盐酸盐用途

5-Aminolevulinic acid盐酸盐是体内血红素生物合成的中间体,为四吡咯的前体。

5-氨基乙酰丙酸盐酸盐名称

[ CAS 号 ]:
5451-09-2

[ 中文名 ]:
5-氨基乙酰丙酸盐酸盐

[ 英文名 ]:
5-Aminolevulinic acid hydrochloride

[中文别名 ]:

[英文别名 ]:

5-Aminolevulinic acid hydrochloride
MFCD00012869
EINECS 226-679-5

5-氨基乙酰丙酸盐酸盐生物活性

[ 描述 ]:

5-Aminolevulinic acid盐酸盐是体内血红素生物合成的中间体,为四吡咯的前体。

[ 相关类别 ]:

信号通路 >> 自噬 >> 自噬

研究领域 >> 代谢疾病

天然产物 >> 其他

[参考文献]

[1]. Stummer, W., et al., Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial. Lancet Oncol, 2006. 7(5): p. 392-401.

[2]. Eyupoglu, I.Y., et al., Improving the extent of malignant glioma resection by dual intraoperative visualization approach. PLoS One, 2012. 7(9): p. e44885.

[相关活性小分子]

5-氨基乙酰丙酸盐酸盐物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
311.5±27.0 °C at 760 mmHg

[ 熔点 ]:
~150 °C (dec.)

[ 分子式 ]:
C₅H₁₀ClNO₃

[ 分子量 ]:
167.59

[ 闪点 ]:
142.2±23.7 °C

[ PSA ]:
80.39000

[ LogP ]:
-0.79

[ 外观性状 ]:
powder

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.482

[ 储存条件 ]:
2-8°C

[ 水溶解性 ]:
H2O: 50 mg/mL

5-氨基乙酰丙酸盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OI1640000

CHEMICAL NAME :: Levulinic acid, 5-amino-, hydrochloride (8CI)

CAS REGISTRY NUMBER :: 5451-09-2

LAST UPDATED :: 199304

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C5-H9-N-O3.Cl-H

MOLECULAR WEIGHT :: 167.61

5-氨基乙酰丙酸盐酸盐安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi,Xn

[ 风险声明 (欧洲) ]:
R36/37/38:Irritating to eyes, respiratory system and skin . R66:Repeated exposure may cause skin dryness or cracking. R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .

[ 安全声明 (欧洲) ]:
S26-S36/37-S37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
OI1640000

[ 海关编码 ]:
2922509090

5-氨基乙酰丙酸盐酸盐合成路线

详细合成路线

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5-氨基乙酰丙酸盐酸盐上游产品

5-氨基乙酰丙酸盐酸盐下游产品

5-氨基乙酰丙酸盐酸盐海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

5-氨基乙酰丙酸盐酸盐文献

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N-3 fatty acids improve body composition and insulin sensitivity during energy restriction in the rat.

Prostaglandins Leukot. Essent. Fatty Acids 91(5) , 203-11, (2014)

The hypothesis that n-3 polyunsaturated fatty acids (PUFA) could contribute to maintain muscle mass during energy restriction aiming to weight loss was tested in the rat, with special attention paid t...

Determination of free fatty acids in human serum by HPLC with fluorescence detection.

J. Chromatogr. Sci. 53 , 537-41, (2015)

It has been suggested that serum concentrations of polyunsaturated essential fatty acids correlate with the symptoms or severity of various diseases, including depression and Alzheimer-type dementia, ...

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