3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one

名称

[ CAS 号 ]:
5496-04-8

[ 英文名 ]:
3-Methyl-1-phenyl-4-(piperidinomethylene)-2-pyrazolin-5-one

[英文别名 ]:

AmbscPOD_15/0510
1-Phenyl-3-methyl-4-piperidinomethylenpyrazolon-5

物理化学性质

[ 密度 ]:
1.18g/cm3

[ 沸点 ]:
375.5ºC at 760 mmHg

[ 分子式 ]:
C₁₆H₁₉N₃O

[ 分子量 ]:
269.34200

[ 闪点 ]:
180.9ºC

[ 精确质量 ]:
269.15300

[ PSA ]:
35.91000

[ LogP ]:
2.21740

[ 折射率 ]:
1.623

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ9651000

CHEMICAL NAME :: 2-Pyrazolin-5-one, 3-methyl-1-phenyl-4-(piperidinomethylene)-

CAS REGISTRY NUMBER :: 5496-04-8

BEILSTEIN REFERENCE NO. :: 0616565

LAST UPDATED :: 199612

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C16-H19-N3-O

MOLECULAR WEIGHT :: 269.38

WISWESSER LINE NOTATION :: T6NTJ A1U- DT5NNVYJ BR& E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 3,17,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CHTPBA Chimica Therapeutica. (Paris, France) V.1-8, 1965-73. For publisher information, see EJMCA5. Volume(issue)/page/year: 3,17,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - analgesia Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 19,1721,1969

安全信息

[ 海关编码 ]:
2933990090

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海关

[ 海关编码 ]: 2933990090

[ 中文概述 ]:
2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%