3-正丁烯基苯酞； 3-亚丁基-1(3H)-异苯并呋喃酮

用途

3-Butylidenephthalide (Butylidenephthalide) 是一种从 Ligusticum chuanxiong Hort 鉴定的邻苯二甲酸酐衍生物,具有杀虫活性 (对 Spodoptera litura larvae 的 LC50 值为 1.56 mg/g)。

名称

[ CAS 号 ]:
551-08-6

[ 中文名 ]:
正丁亚基邻苯二甲酰胺

[ 英文名 ]:
3-Butylidenephthalide

[中文别名 ]:

[英文别名 ]:

1(3H)-Isobenzofuranone, 3-butylidene-, (3Z)-
MFCD00047319
1(3H)-Isobenzofuranone, 3-butylidene-
3-butylidene-3H-isobenzofuran-1-one
Bdph
N-BUTYLIDENEPHTHALIDE
ligusticumlactone
3-Butylidenephtalide
3-butylidene-phthalid
(3Z)-3-Butylidene-2-benzofuran-1(3H)-one

生物活性

[ 描述 ]:

3-Butylidenephthalide (Butylidenephthalide) 是一种从 Ligusticum chuanxiong Hort 鉴定的邻苯二甲酸酐衍生物,具有杀虫活性 (对 Spodoptera litura larvae 的 LC50 值为 1.56 mg/g)。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Yi Y, et al. Z-Ligustilide Exerted Hormetic Effect on Growth and Detoxification Enzymes of Spodoptera lituraLarvae. Evid Based Complement Alternat Med. 2018 Jul 2;2018:7104513.

物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
312.0±35.0 °C at 760 mmHg

[ 分子式 ]:
C₁₂H₁₂O₂

[ 分子量 ]:
188.223

[ 闪点 ]:
127.9±23.4 °C

[ 精确质量 ]:
188.083725

[ PSA ]:
26.30000

[ LogP ]:
3.72

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.631

[ 储存条件 ]:
库房通风低温干燥

MSDS

详细MSDS(安全技术说明书)

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TI3692500

CHEMICAL NAME :: Phthalide, 3-butylidene-

CAS REGISTRY NUMBER :: 551-08-6

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H12-O2

MOLECULAR WEIGHT :: 188.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,659,1983 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1850 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,659,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,659,1983

安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S23

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
TI3692500

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