Urea,N-(2-chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitroso-

名称

[ CAS 号 ]:
56239-24-8

[ 英文名 ]:
Urea,N-(2-chloroethyl)-N'-(trans-4-hydroxycyclohexyl)-N-nitroso-

[英文别名 ]:

物理化学性质

[ 密度 ]:
1.46g/cm3

[ 分子式 ]:
C9H16ClN3O3

[ 分子量 ]:
249.69500

[ 精确质量 ]:
249.08800

[ PSA ]:
82.00000

[ LogP ]:
1.61260

[ 储存条件 ]:
库房低温通风干燥,与食品原料分开存放

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YS4983500
CHEMICAL NAME :
Urea, 1-(2-chloroethyl)-3-(trans-4-hydroxycyclohexyl)-1-nit roso-
CAS REGISTRY NUMBER :
56239-24-8
LAST UPDATED :
199410
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C9-H16-Cl-N3-O3
MOLECULAR WEIGHT :
249.73
WISWESSER LINE NOTATION :
L6TJ AQ DMVNNO&2G -TRANS

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
52420 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD10 - Lethal Dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
12 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intrapleural
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
35 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA damage
TEST SYSTEM :
Human Embryo
DOSE/DURATION :
100 umol/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 44,1352,1984

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