碘丙甘油

碘丙甘油名称

[ CAS 号 ]:
5634-39-9

[ 中文名 ]:
碘丙甘油

[ 英文名 ]:
2-(1-iodoethyl)-1,3-dioxolan-4-ylmethanol

[中文别名 ]:

[英文别名 ]:

碘丙甘油物理化学性质

[ 密度 ]:
1.794g/cm3

[ 沸点 ]:
294.9ºC at 760 mmHg

[ 分子式 ]:
C6H11IO3

[ 分子量 ]:
258.05400

[ 闪点 ]:
132.1ºC

[ 精确质量 ]:
257.97500

[ PSA ]:
38.69000

[ LogP ]:
0.54370

[ 折射率 ]:
1.545

碘丙甘油毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
JI1800000
CHEMICAL NAME :
1,3-Dioxolane-4-methanol, 2-(1-iodoethyl)-
CAS REGISTRY NUMBER :
5634-39-9
LAST UPDATED :
199806
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C6-H11-I-O3
MOLECULAR WEIGHT :
258.07
WISWESSER LINE NOTATION :
T5O COTJ BYI1 D1Q &T5O COTJ B2I D1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6 gm/kg/16D-I
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
32500 mg/kg/13W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
32500 mg/kg/13W-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
64375 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Endocrine - thyroid tumors Blood - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
64375 mg/kg/2Y-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Endocrine - tumors
TYPE OF TEST :
Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
167 mg/L
REFERENCE :
NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-340,1990 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81848 No. of Facilities: 864 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 1099 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81848 No. of Facilities: 85 (estimated) No. of Industries: 2 No. of Occupations: 6 No. of Employees: 854 (estimated) No. of Female Employees: 265 (estimated)

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