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N4-氨基胞苷

N4-氨基胞苷名称

[ CAS 号 ]:
57294-74-3

[ 中文名 ]:
N4-氨基胞苷

[ 英文名 ]:
n4-aminocytidine

[英文别名 ]:

N-Aminocytidine
N4-aminocytidine minimum
N4-NH2-Cr
n(sup4)-aminocytidine
uridine,4-hydrazone

N4-氨基胞苷物理化学性质

[ 密度 ]:
1.93g/cm3

[ 沸点 ]:
555.5ºC at 760mmHg

[ 熔点 ]:
>160 °C(sublime)

[ 分子式 ]:
C₉H₁₆N₄O₅

[ 分子量 ]:
260.24700

[ 闪点 ]:
289.8ºC

[ 精确质量 ]:
260.11200

[ PSA ]:
140.31000

[ 外观性状 ]:
白色至灰白色固体

[ 折射率 ]:
1.776

[ 储存条件 ]:
库房通风低温干燥

N4-氨基胞苷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YU8055000

CHEMICAL NAME :: Uridine, 4-hydrazone

CAS REGISTRY NUMBER :: 57294-74-3

LAST UPDATED :: 199410

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C9-H14-N4-O5

MOLECULAR WEIGHT :: 258.27

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Specific locus test

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 50 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 177,283,1987

N4-氨基胞苷安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H332

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
46-20/21/22

[ 安全声明 (欧洲) ]:
53-22-36/37/39-45

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
YU8055000

[ 海关编码 ]:
29335990

N4-氨基胞苷文献

Genotoxic properties of representatives of alkylindazoles and aminoalkyl-indoles which are consumed as synthetic cannabinoids.

Food Chem. Toxicol. 80 , 130-6, (2015)

Synthetic cannabinoids (SCs) cause similar effects as cannabis and are sold in herbal mixtures. Recent investigations indicate that some of these drugs possess genotoxic properties. Therefore, we test...

Mutagenic nucleoside analog N4-aminocytidine: metabolism, incorporation into DNA, and mutagenesis in Escherichia coli.

J. Bacteriol. 170(11) , 5257-62, (1988)

N4-Aminocytidine, a nucleoside analog, is strongly mutagenic to various organisms including Escherichia coli. Using E. coli WP2 (trp), we measured the incorporation of [5-3H]N4-aminocytidine into DNA ...

An improved synthesis of N4-aminocytidine.

Chem. Pharm. Bull. 35(9) , 3884-7, (1987)

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