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2-羟基-4-(甲硫基)丁酸

2-羟基-4-(甲硫基)丁酸用途

【用途一】
本品是饲料营养强化剂，在L-蛋氨酸存在下其作用和生物效价与DL--蛋氨酸相同。畜禽缺乏蛋氨酸，会引起发育不良、体重减轻、肝肾功能减弱、肌肉萎缩、毛皮变质等。

2-羟基-4-(甲硫基)丁酸名称

[ CAS 号 ]:
583-91-5

[ 中文名 ]:
液态羟基蛋氨酸

[ 英文名 ]:
2-Hydroxy-4-(methylthio)butyric Acid

[中文别名 ]:

[英文别名 ]:

4-methylthio-2-hydroxybutyric acid
MHA acid
DL-2-Hydroxy-4-(methylthio)butyric acid
4-methylmercapto-2-hydroxy-butyric acid
MHA
Butanoic acid,2-hydroxy-4-(methylthio)
EINECS 209-523-0
2-Hydroxy-4-(methylmercapto)butyric Acid
Desmeninol
2-Hydroxy-4-(methylthio)-butanoic Acid

2-羟基-4-(甲硫基)丁酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
316.5±27.0 °C at 760 mmHg

[ 分子式 ]:
C₅H₁₀O₃S

[ 分子量 ]:
150.196

[ 闪点 ]:
145.2±23.7 °C

[ 精确质量 ]:
150.035065

[ PSA ]:
82.83000

[ LogP ]:
0.35

[ 外观性状 ]:
淡棕色液体

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.529

[ 储存条件 ]:
存放于惰性气体之中;避免空气

2-羟基-4-(甲硫基)丁酸MSDS

详细MSDS(安全技术说明书)

2-羟基-4-(甲硫基)丁酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ET4731500

CHEMICAL NAME :: Butyric acid, 2-hydroxy-4-(methylthio)-

CAS REGISTRY NUMBER :: 583-91-5

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C5-H10-O3-S

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3478 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 31(Suppl),54,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83811 No. of Facilities: 92 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 440 (estimated)

2-羟基-4-(甲硫基)丁酸安全信息

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R23/24/25

[ 安全声明 (欧洲) ]:
S26-S36/37/39-S45

[ RTECS号 ]:
ET4731500

2-羟基-4-(甲硫基)丁酸合成路线

详细合成路线

2-羟基-4-(甲硫基)丁酸制备

2. 制备或来源：以丙烯醛为原料，在催化剂作用下同甲硫醇反应，生成的甲硫基丙醛与氢氰酸给催化剂作用合成2-羟基-4甲硫基丁腈，在硫酸存在下水解，经精制得成品。