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非班太尔

非班太尔用途

Febantel是一驱虫剂,用于家禽和家畜的蛔虫、绦虫感染。

非班太尔名称

[ CAS 号 ]:
58306-30-2

[ 中文名 ]:
苯硫胍

[ 英文名 ]:
Febantel

[中文别名 ]:

[英文别名 ]:

Bay h 5757
FEBANTEL PESTANAL
Febantel
rintal
EINECS 261-205-0
Bay h-5757
MFCD01738527
bayvh5757
2-Acetamido-5-nitrothiazole VETRANAL

非班太尔生物活性

[ 描述 ]:

Febantel是一驱虫剂,用于家禽和家畜的蛔虫、绦虫感染。

[ 相关类别 ]:

信号通路 >> 抗感染 >> 寄生物

研究领域 >> 感染

[相关活性小分子]

非班太尔物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 熔点 ]:
129-130ºC

[ 分子式 ]:
C₂₀H₂₂N₄O₆S

[ 分子量 ]:
446.477

[ 精确质量 ]:
446.126007

[ PSA ]:
152.65000

[ LogP ]:
2.36

[ 外观性状 ]:
白色至灰白色粉末

[ 折射率 ]:
1.598

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
水溶性：不溶

非班太尔MSDS

非班太尔毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: FB3955000

CHEMICAL NAME :: Carbamic acid, ((2-((methoxyacetyl)amino)-4-(phenylthio)phenyl)carbo nimidoyl)bis-, dimethyl ester

CAS REGISTRY NUMBER :: 58306-30-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C20-H22-N4-O6-S

MOLECULAR WEIGHT :: 446.52

WISWESSER LINE NOTATION :: 1OVNUYMVO1&MR DSR& BMV1O1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10605 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,2193,1978

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - domestic

DOSE/DURATION :: >200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,2193,1978

非班太尔安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 警示性声明 ]:
P301 + P312 + P330

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R22

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
FB3955000

非班太尔合成路线

非班太尔上下游产品

非班太尔上游产品

非班太尔下游产品

非班太尔文献

Efficacy of a combination of febantel, pyrantel, and praziquantel for the treatment of kittens experimentally infected with Giardia species.

J. Feline Med. Surg. 8(1) , 7-13, (2006)

This study evaluated the effect of two combination products containing febantel, pyrantel, and praziquantel (FPP) for the treatment of Giardia species in experimentally infected kittens. In experiment...

Efficacy of pyrantel embonate, febantel and praziquantel against Giardia species in naturally infected adult dogs.

Vet. Rec. 150(6) , 184-6, (2002)

Rapid determination of the antiparasitic drugs flubendazole and febantel in feeds by HPLC with ultraviolet detection.

J. Pharm. Biomed. Anal. 38(2) , 375-9, (2005)

A rapid and very effective analytical procedure for the simultaneous HPLC determination of two anthelmintics, Flubendazole (FLUB) and Febantel (FEBA), in swine and poultry feeds was developed and test...

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