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达克罗宁

达克罗宁名称

[ CAS 号 ]:
586-60-7

[ 中文名 ]:
达克罗宁

[ 英文名 ]:
Dyclonine

[中文别名 ]:

盐酸达克罗宁

[英文别名 ]:

Dyclocainum
1-(4-butoxyphenyl)-3-piperidin-1-ylpropan-1-one
4'-Butoxy-3-N-piperidino-propiophenon,Dyclon
Diclonina [INN-Spanish]
1-(4-butoxy-phenyl)-3-piperidin-1-yl-propan-1-one
1-(4-butoxyphenyl)-3-(1-piperidinyl)-1-propanone
Dycloninum
Diclonia
Dyclonin
Diclonina

达克罗宁物理化学性质

[ 密度 ]:
1.017g/cm3

[ 沸点 ]:
424.5ºC at 760 mmHg

[ 分子式 ]:
C₁₈H₂₇NO₂

[ 分子量 ]:
289.41200

[ 闪点 ]:
210.5ºC

[ 精确质量 ]:
289.20400

[ PSA ]:
29.54000

[ LogP ]:
3.86210

[ 折射率 ]:
1.517

[ 储存条件 ]:
室温，密闭，干燥

达克罗宁毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UG8672500

CHEMICAL NAME :: Propiophenone, 4'-butoxy-3-piperidino-

CAS REGISTRY NUMBER :: 586-60-7

BEILSTEIN REFERENCE NO. :: 0224037

LAST UPDATED :: 199709

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C18-H27-N-O2

MOLECULAR WEIGHT :: 289.46

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 55 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 18 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 9,38,1962