dl-cis-2-Dimethylamino-1,2,3,4-tetrahydro-1-naphthol benzoate hydrochloride

名称

[ CAS 号 ]:
58782-65-3

[ 英文名 ]:
dl-cis-2-Dimethylamino-1,2,3,4-tetrahydro-1-naphthol benzoate hydrochloride

物理化学性质

[ 分子式 ]:
C19H22ClNO2

[ 分子量 ]:
331.83600

[ 精确质量 ]:
331.13400

[ PSA ]:
29.54000

[ LogP ]:
4.26310

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL5415000
CHEMICAL NAME :
1-Naphthol, 1,2,3,4-tetrahydro-2-dimethylamino-, benzoate, hydrochloride, dl-(Z)-
CAS REGISTRY NUMBER :
58782-65-3
LAST UPDATED :
198803
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C19-H21-N-O2.Cl-H
MOLECULAR WEIGHT :
331.87
WISWESSER LINE NOTATION :
L66&TJ GOVR& HN1&1 &GH -C

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2200 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,842,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
164 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,842,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
14100 ug/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,842,1976

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相关化合物

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