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3'-溴-5'-氯-2'-羟基苯乙酮

3'-溴-5'-氯-2'-羟基苯乙酮名称

[ CAS 号 ]:
59443-15-1

[ 中文名 ]:
3'-溴-5'-氯-2'-羟基苯乙酮

[ 英文名 ]:
3'-bromo-5'-chloro-2'-hydroxyacetophenone

[中文别名 ]:

[英文别名 ]:

MFCD00857068
1-(3-bromo-5-chloro-2-hydroxyphenyl)ethanone

3'-溴-5'-氯-2'-羟基苯乙酮物理化学性质

[ 密度 ]:
1.691g/cm3

[ 沸点 ]:
297.8ºC at 760 mmHg

[ 熔点 ]:
100-103 °C(lit.)

[ 分子式 ]:
C₈H₆BrClO₂

[ 分子量 ]:
249.48900

[ 闪点 ]:
133.9ºC

[ 精确质量 ]:
247.92400

[ PSA ]:
37.30000

[ LogP ]:
3.01070

[ 折射率 ]:
1.604

[ 储存条件 ]:
室温，干燥

3'-溴-5'-氯-2'-羟基苯乙酮MSDS

3'-溴-5'-氯-2'-羟基苯乙酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2914700090

3'-溴-5'-氯-2'-羟基苯乙酮合成路线

3'-溴-5'-氯-2'-羟基苯乙酮上下游产品

3'-溴-5'-氯-2'-羟基苯乙酮上游产品

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3'-溴-5'-氯-2'-羟基苯乙酮海关

[ 海关编码 ]: 2914700090

[ 中文概述 ]:
2914700090 其他酮及醌的卤化、磺化衍生物（包括硝化和亚硝化衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:5.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

3'-溴-5'-氯-2'-羟基苯乙酮文献

Inhibitors and promoters of tubulin polymerization: synthesis and biological evaluation of chalcones and related dienones as potential anticancer agents.

Bioorg. Med. Chem. 19(8) , 2659-65, (2011)

A series of dihalogenated chalcones and structurally related dienones were synthesized and evaluated for their antiproliferative activity in 10 different cancer cell lines and for their effect on micr...

Synthesis of 2-alkyl-substituted chromone derivatives using microwave irradiation.

J. Org. Chem. 74(7) , 2755-9, (2009)

A base-promoted condensation between 2-hydroxyacetophenones and aliphatic aldehydes has been studied. The reaction has been optimized to afford 2-alkyl-substituted 4-chromanones in an efficient manner...

Synthesis and evaluation of substituted chroman-4-one and chromone derivatives as sirtuin 2-selective inhibitors.

J. Med. Chem. 55 , 7104-13, (2012)

A series of substituted chromone/chroman-4-one derivatives has been synthesized and evaluated as novel inhibitors of SIRT2, an enzyme involved in aging-related diseases, e.g., neurodegenerative disord...

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