2,3-戊二酮

2,3-戊二酮用途

2,3-Pentanedione 是合成香料的一种常见成分,用于在饮料、冰淇淋、糖果、烘焙食品、明胶和布丁中提供黄油、草莓、焦糖、水果、朗姆酒或奶酪的香味。2,3-Pentanedione 也作为发酵产物自然存在于啤酒、葡萄酒和酸奶中,并在咖啡豆烘焙过程中释放。

2,3-戊二酮名称

[ CAS 号 ]:
600-14-6

[ 中文名 ]:
2,3-戊二酮

[ 英文名 ]:
2,3-Pentanedione

[中文别名 ]:

[英文别名 ]:

EINECS 209-984-8
MFCD08443597
2,3-Pentadione
2.6-Pentanedione
2,3-PENTANEDITHIOL
3,4-Pentanedione
ethyl methyl diketone
2VV1
PENTANDION-2,3
Acethylpropionyl

2,3-戊二酮生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Morgan DL, et al. Bronchial and bronchiolar fibrosis in rats exposed to 2,3-pentanedione vapors: implications for bronchiolitis obliterans in humans. Toxicol Pathol. 2012;40(3):448-465.

2,3-戊二酮物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
108.0±0.0 °C at 760 mmHg

[ 熔点 ]:
-52 °C

[ 分子式 ]:
C₅H₈O₂

[ 分子量 ]:
100.116

[ 闪点 ]:
18.9±0.0 °C

[ 精确质量 ]:
100.052429

[ PSA ]:
34.14000

[ LogP ]:
-0.80

[ 外观性状 ]:
透明至黄色液体

[ 蒸汽压 ]:
26.4±0.2 mmHg at 25°C

[ 折射率 ]:
1.395

[ 储存条件 ]:
2-8°C

[ 稳定性 ]:
Stable. Highly flammable - store cool. Incompatible with strong oxidizing agents, reducing agents, strong bases.

[ 水溶解性 ]:
60 g/L (15 ºC)

2,3-戊二酮MSDS

2,3-戊二酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SA1850000

CHEMICAL NAME :: 2,3-Pentanedione

CAS REGISTRY NUMBER :: 600-14-6

BEILSTEIN REFERENCE NO. :: 1699638

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C5-H8-O2

MOLECULAR WEIGHT :: 100.13

WISWESSER LINE NOTATION :: 2VV1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,699,1979 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,699,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 17,699,1979

2,3-戊二酮安全信息

[ 符号 ]:

GHS02, GHS07

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H315-H319-H335

[ 警示性声明 ]:
P210-P261-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F:Flammable

[ 风险声明 (欧洲) ]:
R11;R36/37/38

[ 安全声明 (欧洲) ]:
S16-S26-S36-S37/39

[ 危险品运输编码 ]:
UN 1224 3/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
SA1850000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
2914190090

2,3-戊二酮合成路线

2,3-戊二酮上下游产品

2,3-戊二酮上游产品

2,3-戊二酮下游产品

2,3-戊二酮制备

1.天然品存在于芬兰松等精油中，人工合成可在盐酸羟胺存在下，用氮气保护，将甲基丙酮用过量亚硝酸钠和稀盐酸氧化而得。

2.由羟基丙酮与己醛在酸性催化下缩合得到。

2,3-戊二酮海关

[ 海关编码 ]: 2914190090

[ 中文概述 ]:
2914190090 其他不含其他含氧基的无环酮。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 丙酮报明包装

[ Summary ]:
2914190090 other acyclic ketones without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

2,3-戊二酮文献

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To establish the odor profiles of three differently fabricated commercial Swiss Tilsit cheeses, analyses were conducted using headspace solid-phase microextraction gas chromatography-mass spectrometry...

Method development by GC-ECD and HS-SPME-GC-MS for beer volatile analysis.

Food Chem. 167 , 71-7, (2014)

Two methods for the extraction, identification and quantification of the highest occurrence and lowest perception threshold off-flavours in fifteen different samples of Brazilian Pilsner beers were de...

Postmitotic diversification of olfactory neuron types is mediated by differential activities of the HMG-box transcription factor SOX-2.

EMBO J. 34 , 2574-89, (2015)

Diversification of neuron classes is essential for functions of the olfactory system, but the underlying mechanisms that generate individual olfactory neuron types are only beginning to be understood....

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