<生产厂家价格>

8-硝基喹啉

8-硝基喹啉用途

【用途一】
用于有机合成。

8-硝基喹啉名称

[ CAS 号 ]:
607-35-2

[ 中文名 ]:
8-硝基喹啉

[ 英文名 ]:
8-Nitroquinoline

[中文别名 ]:

8-硝基氮杂萘

[英文别名 ]:

Quinoline, 8-nitro-
EINECS 210-135-9
8-Nitroquinoline
MFCD00006806

8-硝基喹啉物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
323.1±17.0 °C at 760 mmHg

[ 熔点 ]:
89-91 °C(lit.)

[ 分子式 ]:
C₉H₆N₂O₂

[ 分子量 ]:
174.156

[ 闪点 ]:
149.2±20.9 °C

[ 精确质量 ]:
174.042923

[ PSA ]:
58.71000

[ LogP ]:
1.47

[ 外观性状 ]:
淡黄色晶体

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.682

[ 储存条件 ]:
室温

8-硝基喹啉MSDS

详细MSDS(安全技术说明书)

8-硝基喹啉毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VC1925000

CHEMICAL NAME :: Quinoline, 8-nitro-

CAS REGISTRY NUMBER :: 607-35-2

BEILSTEIN REFERENCE NO. :: 0135178

LAST UPDATED :: 199710

DATA ITEMS CITED :: 10

MOLECULAR FORMULA :: C9-H6-N2-O2

MOLECULAR WEIGHT :: 174.17

WISWESSER LINE NOTATION :: T66 BNJ JNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17 gm/kg/48W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Gastrointestinal - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 gm/kg/48W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Gastrointestinal - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 43680 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 36400 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Reproductive - Tumorigenic effects - ovarian tumors

MUTATION DATA

TYPE OF TEST :: DNA repair

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 350 ug/disc

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 39,285,1977

8-硝基喹啉安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302 + H312 + H332-H315-H319-H335-H351

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R36/37/38;R40;R68

[ 安全声明 (欧洲) ]:
S26-S27-S36/37/39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
VC1925000

8-硝基喹啉上下游产品

8-硝基喹啉上游产品

8-硝基喹啉下游产品

8-硝基喹啉制备

二、制备方法：由邻硝基苯胺与甘油在五氧化二砷和硫酸存在下，于130-135℃反应7-8h，环合即得8-硝基喹啉。

8-硝基喹啉文献

[Studies on the tissue schizonticide of malaria parasite: synthesis of derivatives of 2-substituted phenoxyprimaquine, 4-methylprimaquine and quinoxaline].

Yao Xue Xue Bao 27(6) , 418-22, (1992)

2-Substituted phenoxy-, 4-methyl-6-methoxy-8-aminoquinolines and 7-methoxy-5-aminoquinoxaline were condensed with 1-phthalimido-bromo-alkane to yield 2-substituted phenoxy-, 4-methyl-6-methoxy-8-(1-ph...

[Formations and reactions of aromatic furazan compounds].

Yakugaku Zasshi 121(6) , 379-93, (2001)

A reaction from various kinds of nitroquinoline with hydroxylamine in potassium hydroxide alkalinity produced a novel product, furazanoquinoline, besides the known amino derivatives. The products obta...

更多文献