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2-硝基芴

2-硝基芴用途

【用途一】
有机合成中间体。

2-硝基芴名称

[ CAS 号 ]:
607-57-8

[ 中文名 ]:
2-硝基芴

[ 英文名 ]:
2-Nitro-9H-fluorene

[中文别名 ]:

[英文别名 ]:

2-Nitro-9H-fluorene
EINECS 210-138-5
MFCD00001117
9H-Fluorene, 2-nitro-
2-Nitrofluorene
L B656 HHJ ENW

2-硝基芴物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
374.7±21.0 °C at 760 mmHg

[ 熔点 ]:
156-158 °C(lit.)

[ 分子式 ]:
C₁₃H₉NO₂

[ 分子量 ]:
211.216

[ 闪点 ]:
185.2±14.9 °C

[ 精确质量 ]:
211.063324

[ PSA ]:
45.82000

[ LogP ]:
3.89

[ 外观性状 ]:
奶油色粉末

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.677

[ 储存条件 ]:
室温

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents.

[ 水溶解性 ]:
Insoluble

2-硝基芴MSDS

详细MSDS(安全技术说明书)

2-硝基芴毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LL8225000

CHEMICAL NAME :: 9H-Fluorene, 2-nitro-

CAS REGISTRY NUMBER :: 607-57-8

BEILSTEIN REFERENCE NO. :: 1877983

LAST UPDATED :: 199710

DATA ITEMS CITED :: 44

MOLECULAR FORMULA :: C13-H9-N-O2

MOLECULAR WEIGHT :: 211.23

WISWESSER LINE NOTATION :: L B656 HHJ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3400 mg/kg/23W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 310 mg/kg/79W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors Endocrine - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4000 mg/kg

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors

TYPE OF TEST :: Morphological transformation

TYPE OF TEST :: DNA adduct

TYPE OF TEST :: Unscheduled DNA synthesis

TYPE OF TEST :: Sister chromatid exchange

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 10 umol/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,1,1982 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,277,1989 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,277,1989 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 46,291,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7137 No. of Facilities: 75 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 149 (estimated)

2-硝基芴安全信息

[ 符号 ]:

GHS08, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H351-H411

[ 警示性声明 ]:
P273-P281

[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
Xn:Harmful;

[ 风险声明 (欧洲) ]:
R40;R68

[ 安全声明 (欧洲) ]:
S36/37-S61

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
LL8225000

[ 危险类别 ]:
9.0

[ 海关编码 ]:
29042000

2-硝基芴上下游产品

2-硝基芴上游产品

2-硝基芴下游产品

2-硝基芴制备

二、制备方法：将60g芴和500ml冰乙酸混匀，搅拌加热至50℃，滴加80ml浓硝酸。加热至80℃反应5min，冷至室温，滤出生成的2-硝基芴，用冷的冰乙酸洗涤、水洗，冰乙酸重结晶，得56g纯品，收率79%。

2-硝基芴海关

[ 海关编码 ]: 2904209090

[ 中文概述 ]:
2904209090 其他仅含硝基或亚硝基的衍生物。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2904209090 derivatives containing only nitro or only nitroso groups。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

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