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N-甲基 -n-亚硝基-(2-甲基苯基)甲胺

N-甲基 -n-亚硝基-(2-甲基苯基)甲胺名称

[ CAS 号 ]:
62783-48-6

[ 中文名 ]:
N-甲基 -n-亚硝基-(2-甲基苯基)甲胺

[ 英文名 ]:
Benzenemethanamine,N,2-dimethyl-N-nitroso-

[英文别名 ]:

Benzylamine,o-dimethyl-N-nitroso
BENZYLAMINE,N,o-DIMETHYL-N-NITROSO

N-甲基 -n-亚硝基-(2-甲基苯基)甲胺物理化学性质

[ 密度 ]:
1.02g/cm3

[ 沸点 ]:
316.7ºC at 760 mmHg

[ 分子式 ]:
C₉H₁₂N₂O

[ 分子量 ]:
164.20400

[ 闪点 ]:
145.3ºC

[ 精确质量 ]:
164.09500

[ PSA ]:
32.67000

[ LogP ]:
2.10820

[ 折射率 ]:
1.524

[ 储存条件 ]:
室温，密封，干燥

N-甲基 -n-亚硝基-(2-甲基苯基)甲胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DP4760000

CHEMICAL NAME :: Benzylamine, N,o-dimethyl-N-nitroso-

CAS REGISTRY NUMBER :: 62783-48-6

LAST UPDATED :: 199203

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H12-N2-O

MOLECULAR WEIGHT :: 164.23

WISWESSER LINE NOTATION :: ONN1&1R B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 90 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - chromodacryorrhea Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. (Berlin, Fed. Rep. Ger.) V.76-92, 1971-78. For publisher information, see JCROD7. Volume(issue)/page/year: 88,231,1977 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg/29W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

REFERENCE :: ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie. (Berlin, Fed. Rep. Ger.) V.76-92, 1971-78. For publisher information, see JCROD7. Volume(issue)/page/year: 88,231,1977

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 31640 mg/kg/2Y-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

REFERENCE :: JCROD7 Journal of Cancer Research and Clinical Oncology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.93- 1979- Volume(issue)/page/year: 95,123,1979