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己二酰二胺

己二酰二胺用途

有机合成。

己二酰二胺名称

[ CAS 号 ]:
628-94-4

[ 中文名 ]:
已二酰二胺

[ 英文名 ]:
adipamide

[中文别名 ]:

[英文别名 ]:

adipic acid bisamide
HSDB 5510
Adipic acid amide
Adipic acid diamide
CCRIS 5883
Adipic diamide
Adipamide
1,4-Butanedicarboxamide
Adipinsaeurediamid
MFCD00008045

己二酰二胺物理化学性质

[ 密度 ]:
1.18g/cm3

[ 沸点 ]:
412.4ºC at 760 mmHg

[ 熔点 ]:
226-229 °C(lit.)

[ 分子式 ]:
C₆H₁₂N₂O₂

[ 分子量 ]:
144.17200

[ 闪点 ]:
203.2ºC

[ 精确质量 ]:
144.09000

[ PSA ]:
86.18000

[ LogP ]:
0.91800

[ 外观性状 ]:
粉末

[ 折射率 ]:
1.48

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

己二酰二胺MSDS

己二酰二胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7800000

CHEMICAL NAME :: Adipamide

CAS REGISTRY NUMBER :: 628-94-4

BEILSTEIN REFERENCE NO. :: 1762331

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H12-N2-O2

MOLECULAR WEIGHT :: 144.20

WISWESSER LINE NOTATION :: ZV4VZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 90,260,1947

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 34,1196,1940 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1270 mg/kg/1Y-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

REFERENCE :: JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 3(5-6),149,1980

己二酰二胺安全信息

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
AU7800000

己二酰二胺合成路线

己二酰二胺上下游产品

己二酰二胺上游产品

己二酰二胺下游产品

己二酰二胺文献

Carcinogenesis bioassay of acetamide, hexanamide, adipamide, urea and P-tolylurea in mice and rats.

J. Environ. Pathol. Toxicol. 3(5-6) , 149-70, (1980)

As a part of the National Cancer Institute's effort to screen environmental and occupational chemicals for chronic toxicity and carcinogenicity, the amides acetamide, hexanamide, adipamide, urea, and ...

The preparation of nylon-tube-supported hexokinase and glucose 6-phosphate dehydrogenase and the use of the co-immobilized enzymes in the automated determination of glucose.

Biochem. J. 147(3) , 593-603, (1975)

Triethyloxonium tetrafluoroborate was used to O-alkylate nylon-tube thus producing the imidate salt of the nylon which was further made to react with 1,6-diaminohexane. 2. Hexokinase (EC 2.7.1.1) and ...

Development of biomimetic nano-hydroxyapatite/poly(hexamethylene adipamide) composites.

Biomaterials 23(24) , 4787-91, (2002)

In this study, acicular nano-hydroxyapatite (n-HA) was used to make a new biomimetic composite with polyamide (poly hexamethylene adipamide) by a unique technique. The physical and chemical characteri...

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