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(R)-异丝氨酸

(R)-异丝氨酸用途

(S)-异丝氨酸是一种具有生物活性的β-氨基酸和重要的医药中间体。

(R)-异丝氨酸名称

[ CAS 号 ]:
632-11-1

[ 中文名 ]:
(R)-异丝氨酸

[ 英文名 ]:
(2S)-3-Amino-2-hydroxypropanoic acid

[英文别名 ]:

5-Oxo-L-proline 1-methylethyl ester
L-Pyroglutamic acid isopropyl ester
isopropyl 5-oxo-L-prolinate
pyroglutamic acid iso-propyl ester
Propanoic acid, 3-amino-2-hydroxy-, (2S)-
Propanoic acid, 3-amino-2-hydroxy-, (2R)-
(2R)-3-Amino-2-hydroxypropanoic acid
(2S)-3-Amino-2-hydroxypropanoic acid

(R)-异丝氨酸物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
386.6±27.0 °C at 760 mmHg

[ 分子式 ]:
C₃H₇NO₃

[ 分子量 ]:
105.093

[ 闪点 ]:
187.6±23.7 °C

[ 精确质量 ]:
105.042595

[ PSA ]:
83.55000

[ LogP ]:
-0.97

[ 蒸汽压 ]:
0.0±2.0 mmHg at 25°C

[ 折射率 ]:
1.519

[ 储存条件 ]:
2-8°C，避光，惰性气体

(R)-异丝氨酸安全信息

[ 危害码 (欧洲) ]:
Xi

(R)-异丝氨酸文献

Novel parent structures for inhibitors of the murine GABA transporters mGAT3 and mGAT4.

Eur. J. Pharmacol. 519(1-2) , 43-7, (2005)

Searching for potent and subtype selective parent structures of the murine gamma-aminobutyric acid (GABA) transporter subtypes mGAT3 and mGAT4 a series of amino acids was characterised in a uniform [3...

Glycine conjugates in a lepidopteran insect herbivore--the metabolism of benzylglucosinolate in the cabbage white butterfly, Pieris rapae.

ChemBioChem. 7(12) , 1982-9, (2006)

Herbivores have developed a wide array of countermeasures to overcome plants' chemical defences. Larvae of the cabbage white butterfly, Pieris rapae, feed exclusively on plants of the Brassicales orde...

Microbial resolution of 2-hydroxy-3-nitropropionic acid for synthesis of optically active isoserine.

Biosci. Biotechnol. Biochem. 65(5) , 1258-60, (2001)

The biocatalytic stereoselective hydrolysis of 2-hydroxy-3-nitropropionic acid esters was studied. Forty enzymes and three hundred microorganism strains were examined for their ability to hydrolyze et...

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