N(delta)-(N-methyl-N-nitrosocarbamoyl)-L-ornithine

名称

[ CAS 号 ]:
63642-17-1

[ 英文名 ]:
N(delta)-(N-methyl-N-nitrosocarbamoyl)-L-ornithine

[英文别名 ]:

N(sup 5)-(Methylnitrosocarbamoyl)-L-ornithine
N-(N-Methyl-N-nitrosocarbamoyl)-l-ornithine
n5-[methyl(nitroso)carbamoyl]-l-ornithine
L-Ornithine,N(5)-((methylnitrosoamino)carbonyl)
N5-((Methylnitrosoamino)carbonyl)-L-ornithine
MNCO

物理化学性质

[ 分子式 ]:
C₇H₁₄N₄O₄

[ 分子量 ]:
218.21000

[ 精确质量 ]:
218.10200

[ PSA ]:
128.58000

[ LogP ]:
0.40600

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RM2983000

CHEMICAL NAME :: L-Ornithine, N(sup 5)-(N-methyl-N-nitrosocarbamoyl)-,

CAS REGISTRY NUMBER :: 63642-17-1

LAST UPDATED :: 199310

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C7-H14-N4-O4

MOLECULAR WEIGHT :: 218.25

WISWESSER LINE NOTATION :: QVYZ3MVN1&NO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1870 mg/kg/26W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 2616 mg/kg/12W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 3924 mg/kg/6W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - hamster

DOSE/DURATION :: 1308 mg/kg/6W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: DNA damage

MUTATION DATA

TEST SYSTEM :: Rodent - hamster

DOSE/DURATION :: 25 mg/kg

REFERENCE :: CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,1033,1987 *** REVIEWS *** TOXICOLOGY REVIEW APLMAS Archives of Pathology and Laboratory Medicine. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1-5(2), 1926-28; V.100- 1976- Volume(issue)/page/year: 107,54,1983

安全信息

[ 海关编码 ]:
2924199090

海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%