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4,4-五亚甲基-2-吡咯烷酮

4,4-五亚甲基-2-吡咯烷酮用途

【用途一】
用作药物加巴喷丁中间体

4,4-五亚甲基-2-吡咯烷酮名称

[ CAS 号 ]:
64744-50-9

[ 中文名 ]:
3,3'-亚戊烯基-4-丁内酰胺

[ 英文名 ]:
Gabapentin-lactam

[中文别名 ]:

[英文别名 ]:

Pentamethylene pyrrolidinone
4,4-pentamethylene-2-pyrrolidone
2-AZASPIRO-(4,5)-DECAN-3-ONE
3,3-Pentamethylene-4-butyrolac
3,3-Pentenylene-4-butyrolactam
Gabapentin Related Compound A
4,4-Pentamethylene-2-pyrrolidinone
MFCD00177938
GABA-pentinlactam
EINECS 451-630-1

4,4-五亚甲基-2-吡咯烷酮物理化学性质

[ 密度 ]:
1.05 g/cm3

[ 沸点 ]:
181 °C / 13mmHg

[ 熔点 ]:
84-89 °C(lit.)

[ 分子式 ]:
C₉H₁₅NO

[ 分子量 ]:
153.22100

[ 闪点 ]:
192.3ºC

[ 精确质量 ]:
153.11500

[ PSA ]:
29.10000

[ LogP ]:
1.78560

[ 外观性状 ]:
白色固体

[ 折射率 ]:
1.509

[ 储存条件 ]:
-20°C Freezer

[ 水溶解性 ]:
可溶于：甲醇

4,4-五亚甲基-2-吡咯烷酮MSDS

4,4-五亚甲基-2-吡咯烷酮毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CM0120000

CHEMICAL NAME :: 2-Azaspiro(4,5)decan-3-one

CAS REGISTRY NUMBER :: 64744-50-9

BEILSTEIN REFERENCE NO. :: 0119500

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H15-N-O

MOLECULAR WEIGHT :: 153.25

WISWESSER LINE NOTATION :: T5MV DXTJ D-& AL6XTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 125 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,243,1960

4,4-五亚甲基-2-吡咯烷酮安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
CM0120000

[ 海关编码 ]:
2933790090

4,4-五亚甲基-2-吡咯烷酮合成路线

4,4-五亚甲基-2-吡咯烷酮上下游产品

4,4-五亚甲基-2-吡咯烷酮上游产品

4,4-五亚甲基-2-吡咯烷酮下游产品

4,4-五亚甲基-2-吡咯烷酮海关

[ 海关编码 ]: 2933790090

[ 中文概述 ]:
2933790090 其他内酰胺. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:9.0% 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

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