N-[6-[[(1S,3S)-3-(1,2-dihydroxyethyl)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyl-oxan-4-yl]-2,2,2-trifluoro-acetamide

名称

[ 英文名 ]:
N-[6-[[(1S,3S)-3-(1,2-dihydroxyethyl)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyl-oxan-4-yl]-2,2,2-trifluoro-acetamide

[英文别名 ]:

N-trifluoroacetyladriamycinol
AD-92

物理化学性质

[ 密度 ]:
1.66g/cm3

[ 沸点 ]:
872.9ºC at 760 mmHg

[ 分子式 ]:
C₂₉H₃₀F₃NO₁₂

[ 分子量 ]:
641.54300

[ 闪点 ]:
481.7ºC

[ 精确质量 ]:
641.17200

[ PSA ]:
212.31000

[ LogP ]:
0.90380

[ 折射率 ]:
1.662

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QI9420000

CHEMICAL NAME :: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-8-(1,2-dihydroxyethyl)-1-methoxy- 10-((2,3,6- trideoxy-2-(trifluoroacetamido)-alpha-L-lyxo-hexopyra nosyl)oxy)-6,8,11-tri hydroxy-

CAS REGISTRY NUMBER :: 66512-17-2

LAST UPDATED :: 198207

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C29-H30-F3-N-O12

MOLECULAR WEIGHT :: 641.60

WISWESSER LINE NOTATION :: L E6 C666 BV MVT&&&J DQ HYQ1Q HQ KQ RO1 FO- FT6OTJ B1 CQ DMVXFFF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 43700 nmol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 41,1006,1981