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4-(氨甲基)环己甲酸

4-(氨甲基)环己甲酸名称

[ CAS 号 ]:
701-54-2

[ 中文名 ]:
凝血酸

[ 英文名 ]:
Tranexamic acid

[中文别名 ]:

[英文别名 ]:

1-(biphenyl-4-yl)methanamine
4-aminomethylcyclohexane-1-carboxylic acid
(4-phenylphenyl)methylamine
4-(Aminomethyl)-Cyclohexanecarboxylic Acid
4-aminomethylbiphenyl
4-Aminomethyl-cyclohexancarbonsaeure
4-Aminomethyl-cyclohexanecarboxylic acid
4-Biphenylmethylamine
4-(Aminomethyl)cyclohexanecarboxylic acid
[1,1'-biphenyl]-4-yl methanamine

4-(氨甲基)环己甲酸物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
300.2±15.0 °C at 760 mmHg

[ 熔点 ]:
233ºC

[ 分子式 ]:
C₈H₁₅NO₂

[ 分子量 ]:
157.210

[ 闪点 ]:
135.4±20.4 °C

[ 精确质量 ]:
157.110275

[ PSA ]:
63.32000

[ LogP ]:
0.31

[ 蒸汽压 ]:
0.0±1.3 mmHg at 25°C

[ 折射率 ]:
1.497

[ 储存条件 ]:
Refrigerator

4-(氨甲基)环己甲酸MSDS

详细MSDS(安全技术说明书)

4-(氨甲基)环己甲酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GU8399950

CHEMICAL NAME :: Cyclohexanecarboxylic acid, 4-(aminomethyl)-

CAS REGISTRY NUMBER :: 701-54-2

LAST UPDATED :: 199509

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C8-H15-N-O2

MOLECULAR WEIGHT :: 157.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >15 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 32500 mg/kg/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Blood - changes in leukocyte (WBC) count Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases

REFERENCE :: APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 22,340,1965

4-(氨甲基)环己甲酸安全信息

[ RTECS号 ]:
GU8399950

[ 海关编码 ]:
2922499990

4-(氨甲基)环己甲酸海关

[ 海关编码 ]: 2922499990

[ 中文概述 ]:
2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%