BUCINDOLOL
BUCINDOLOL名称
[ CAS 号 ]:
70369-47-0
[ 英文名 ]:
BUCINDOLOL
[英文别名 ]:
- Bucindolol HCl
- Bucindolol hydrochloride
- Bucindolol hydrochloride (USAN)
BUCINDOLOL物理化学性质
[ 沸点 ]:
605.3ºC at 760 mmHg
[ 分子式 ]:
C22H25N3O2
[ 分子量 ]:
363.45300
[ 闪点 ]:
319.9ºC
[ 精确质量 ]:
363.19500
[ PSA ]:
81.07000
[ LogP ]:
3.78108
BUCINDOLOL毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DI4605000
- CHEMICAL NAME :
- Benzonitrile, 2-(2-hydroxy-3-((2-(1H-indol-3-yl)-1,1-dimethylethyl) amino)propoxy)-, monohydrochloride
- CAS REGISTRY NUMBER :
- 70369-47-0
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H25-N3-O2.Cl-H
- MOLECULAR WEIGHT :
- 399.96
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2, 1983-84. For publisher information, see NCDREP. Volume(issue)/page/year: 1,1,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - somnolence (general depressed activity) Behavioral - ataxia
- REFERENCE :
- NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2, 1983-84. For publisher information, see NCDREP. Volume(issue)/page/year: 1,1,1983
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