N,N-二甲基-γ-(4-氯苯基)-2-吡啶丙胺顺丁烯二酸盐
名称
[ CAS 号 ]:
7054-11-7
[ 中文名 ]:
N,N-二甲基-γ-(4-氯苯基)-2-吡啶丙胺顺丁烯二酸盐
[ 英文名 ]:
CHLORPHENAMINE MALEATES
[中文别名 ]:
[英文别名 ]:
- chlorphenamine maleate
- chloropheniramine maleate
- chlortrimeton
物理化学性质
[ 熔点 ]:
130-135ºC(lit.)
[ 分子式 ]:
C20H23ClN2O4
[ 分子量 ]:
390.86100
[ 精确质量 ]:
390.13500
[ PSA ]:
90.73000
[ LogP ]:
3.14170
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US6503000
- CAS REGISTRY NUMBER :
- 7054-11-7
- LAST UPDATED :
- 199806
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C16-H19-Cl-N2.C4-H4-O4
- MOLECULAR WEIGHT :
- 390.90
- WISWESSER LINE NOTATION :
- T6NJ BYR DG&2N1&1 &QV1U1VQ -+-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 118 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 89 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 121 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 73 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 265 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 500 umol/L
- REFERENCE :
- EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 24,181,1994
安全信息
[ 危害码 (欧洲) ]:
T,Xi
[ 风险声明 (欧洲) ]:
25-36/37/38
[ 安全声明 (欧洲) ]:
36/37/39-45-36-26
[ 危险品运输编码 ]:
UN 2811 6.1/PG 3
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相关化合物
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