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依地芬

依地芬用途

依地福新是一种合成烷基-赖氨磷脂,具有抗肿瘤活性。该化合物诱导多种癌细胞的凋亡。乙二胺嘧啶在细胞膜中积累,在细胞膜中改变脂质成分并诱导脂质筏和 Fas/CD95 死亡受体的共簇。

依地芬名称

[ CAS 号 ]:
70641-51-9

[ 中文名 ]:
依地福新

[ 英文名 ]:
Edelfosine

[英文别名 ]:

依地芬物理化学性质

[ 分子式 ]:
C27H58NO6P

[ 分子量 ]:
523.726

[ 精确质量 ]:
523.400146

[ PSA ]:
86.86000

[ LogP ]:
4.65

[ 外观性状 ]:
蜡质固体

[ 储存条件 ]:
20°C

依地芬MSDS

依地芬毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YK0718000
CHEMICAL NAME :
3,5,9-Trioxa-4-phosphaheptacosan-1-aminium, 4-hydroxy-7-methoxy-N,N,N-trimethyl-, hydroxide, inner salt, 4-oxide, (+-)-
CAS REGISTRY NUMBER :
70641-51-9
LAST UPDATED :
199612
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C27-H58-N-O6-P
MOLECULAR WEIGHT :
523.83

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA inhibition
TEST SYSTEM :
Human Cells - not otherwise specified
DOSE/DURATION :
1 mg/L
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,5538,1983

依地芬安全信息

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

依地芬合成路线

依地芬上下游产品

依地芬文献

Coculture of peripheral blood-derived mesenchymal stem cells and endothelial progenitor cells on strontium-doped calcium polyphosphate scaffolds to generate vascularized engineered bone.

Tissue Eng. Part A 21(5-6) , 948-59, (2015)

Vascularization of engineered bone tissue is critical for ensuring its survival after implantation and it is the primary factor limiting its clinical use. A promising approach is to prevascularize bon...

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage.

PLoS ONE 9(10) , e111059, (2014)

Mesenchymal stem cells (MSCs) are viewed as safe, readily available and promising adult stem cells, which are currently used in several clinical trials. Additionally, their soluble-factor secretion an...

Knock-down of p300 decreases the proliferation and odontogenic differentiation potentiality of HDPCs.

Int. Endod. J. 48 , 976-85, (2015)

To investigate the role of p300 in the regulation of proliferation and odontogenic differentiation of human dental pulp cells (HDPCs).The recombinant lentiviral vector pshRNA-copGFP was used to knock-...


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区域:上海市普陀区

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联系人:徐经理

产品详情:依地芬


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相关化合物

【依地芬】化源网提供依地芬CAS号70641-51-9,依地芬MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询依地芬上化源网,专业又轻松。>>电脑版:依地芬

标题:依地芬_MSDS_用途_分子量_依地芬CAS号【70641-51-9】_化源网 地址:https://www.chemsrc.com/amp/cas/70641-51-9_524809.html