10-[4-(dibenzylamino)-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride

名称

[ 英文名 ]:
10-[4-(dibenzylamino)-5-hydroxy-6-methyl-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione hydrochloride

[英文别名 ]:

Dibenzyladriamycin hydrochloride
N,N-Dibenzyladriamycin hydrochloride

物理化学性质

[ 密度 ]:
1.48g/cm3

[ 沸点 ]:
902.9ºC at 760 mmHg

[ 分子式 ]:
C₄₁H₄₂ClNO₁₁

[ 分子量 ]:
760.22500

[ 闪点 ]:
499.8ºC

[ 精确质量 ]:
759.24500

[ PSA ]:
183.29000

[ LogP ]:
4.54700

[ 折射率 ]:
1.71

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: QI9340000

CHEMICAL NAME :: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-10-((3-(bis(phenylmethyl)amino)-2 ,3,6-trideoxy- alpha-L-lyxo-hexopyranosyl)oxy)-8-(hydroxyacetyl)-1-m ethoxy-6,8,11-trihydr oxy-, hydrochloride, (8S-cis)-

CAS REGISTRY NUMBER :: 70844-20-1

LAST UPDATED :: 198509

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C41-H41-N-O11.Cl-H

MOLECULAR WEIGHT :: 760.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Leukocyte

DOSE/DURATION :: 4800 nmol/L

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 22,912,1979