1-nitro-2-nitroso-1-propylguanidine

1-nitro-2-nitroso-1-propylguanidine名称

[ CAS 号 ]:
71598-10-2

[ 英文名 ]:
1-nitro-2-nitroso-1-propylguanidine

[英文别名 ]:

1-nitro-2-nitroso-1-propylguanidine物理化学性质

[ 密度 ]:
1.514g/cm3

[ 沸点 ]:
295.815ºC at 760 mmHg

[ 分子式 ]:
C4H9N5O3

[ 分子量 ]:
175.14600

[ 闪点 ]:
132.704ºC

[ 精确质量 ]:
175.07100

[ PSA ]:
117.86000

[ LogP ]:
1.28920

[ 折射率 ]:
1.594

1-nitro-2-nitroso-1-propylguanidine毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MF4640000
CHEMICAL NAME :
Guanidine, 1-nitro-3-nitroso-1-propyl-
CAS REGISTRY NUMBER :
71598-10-2
LAST UPDATED :
199612
DATA ITEMS CITED :
14
MOLECULAR FORMULA :
C4-H9-N5-O3
MOLECULAR WEIGHT :
175.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2172 mg/kg/52W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
60 mg/kg/5W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2172 mg/kg/52W-C
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3080 mg/kg/44W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
3665 mg/kg/44W-C
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
TYPE OF TEST :
DNA damage
TYPE OF TEST :
Unscheduled DNA synthesis

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
10 mg/L
REFERENCE :
GMCRDC Gann Monograph on Cancer Research. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No. 11- 1971- Volume(issue)/page/year: 27,95,1981

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