(+)-PENTAZOCINE-DEA SCHEDULE IV ITEM

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
403.5±45.0 °C at 760 mmHg

[ 分子式 ]:
C₁₉H₂₇NO

[ 分子量 ]:
285.424

[ 闪点 ]:
180.8±27.4 °C

[ 精确质量 ]:
285.209259

[ LogP ]:
4.53

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.554

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H312-H332

[ 警示性声明 ]:
P280

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危险品运输编码 ]:
NONH for all modes of transport

Allosteric modulation of sigma-1 receptors elicits anti-seizure activities.

Br. J. Pharmacol. 172 , 4052-65, (2015)

Application of orthosteric sigma-1 receptor agonists as anti-seizure drugs has been hindered by questionable efficacy and potential adverse effects. Here, we have investigated the anti-seizure effects...

Involvement of hypothalamic neuropeptide Y in pentazocine induced suppression of food intake in rats.

Neuropeptides 48(3) , 133-41, (2014)

The potent orexigenic peptide neuropeptide Y (NPY) has been considered as a possible endogenous ligand for a subpopulation of sigma receptors (SigR). However, their mutual interaction with reference t...

Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.

J. Med. Chem. 57(24) , 10404-23, (2014)

The discovery and synthesis of a new series of pyrimidines as potent sigma-1 receptor (σ1R) antagonists, associated with pharmacological antineuropathic pain activity, are the focus of this article. T...

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