阿托品硫酸盐

阿托品硫酸盐名称

[ CAS 号 ]:
73791-47-6

[ 中文名 ]:
阿托品硫酸盐

[ 英文名 ]:
atropine sulfate

[英文别名 ]:

MFCD00077268
atropine sulphate
EINECS 200-235-0

阿托品硫酸盐物理化学性质

[ 沸点 ]:
429.8ºC at 760 mmHg

[ 熔点 ]:
189-192ºC (A)(lit.)

[ 分子式 ]:
C₁₇H₂₅NO₇S

[ 分子量 ]:
387.44800

[ 闪点 ]:
213.7ºC

[ 精确质量 ]:
387.13500

[ PSA ]:
132.75000

[ LogP ]:
2.29680

阿托品硫酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CK2455000

CAS REGISTRY NUMBER :: 73791-47-6

LAST UPDATED :: 198702

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C34-H46-N2-O6.H2-O4-S.H2-O

MOLECULAR WEIGHT :: 694.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraduodenal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 25,1037,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 723 mg/kg

TOXIC EFFECTS :: Behavioral - excitement Lungs, Thorax, or Respiration - respiratory stimulation Skin and Appendages - hair

REFERENCE :: TOIZAG Toho Igakkai Zasshi. Journal of Medical Society of Toho University. (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143, Japan) V.1- 1954- Volume(issue)/page/year: 17,60,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#03400

阿托品硫酸盐安全信息

[ 危害码 (欧洲) ]:
T+: Very toxic;

[ 风险声明 (欧洲) ]:
R26/28

[ 安全声明 (欧洲) ]:
23-45

[ 危险品运输编码 ]:
UN 1544 6

[ WGK德国 ]:
2